Table 1.
Baseline characteristics of all randomized children for each treatment arm.
| Solid N = 198 | Chewable N = 198 | |
|---|---|---|
| Mean age [years] | 9.3 (2.1) | 9.4 (2.1) |
| Girls | 80 (40.4) | 88 (44.2) |
| Mean weight [kg] | 26.0 (6.6) | 25.4 (6.3) |
| Mean height [cm] | 130.8 (11.6) | 130.5 (11.6) |
| Children aged ≤ 5 | 10 (5.1) | 7 (3.5) |
| Children aged >5 | 188 (94.9) | 191 (94.5) |
| Hookworm | ||
| EPG median | 192 (102–402) | 165 (96–402) |
| EPG geometric mean | 224.9 | 218.0 |
| EPG arithmetic mean | 427.0 | 441.2 |
| Minimum EPG | 54 | 54 |
| Maximum EPG | 9180 | 7524 |
| Infection intensity | ||
| Light (1–1999 EPG) | 192 (97) | 191 (96) |
| Moderate (2000–3999 EPG) | 4 (2) | 5 (3) |
| Heavy (≥4000 EPG) | 2 (1) | 2 (1) |
| Trichuris trichiura | ||
| Infected children | 195 | 195 |
| EPG median | 540 (273–1338) | 600 (234–1446) |
| EPG geometric mean | 633.5 | 584.6 |
| EPG arithmetic mean | 1,040.0 | 1,257.0 |
| Minimum EPG | 0 | 0 |
| Maximum EPG | 19,362 | 15,894 |
| Infection intensity | ||
| Light (1–999 EPG) | 126 (64) | 118 (61) |
| Moderate (1000–9999 EPG) | 68 (35) | 75 (38) |
| Heavy (≥10,000 EPG) | 1 (1) | 2 (1) |
| Ascaris lumbricoides | ||
| Infected children | 91 | 107 |
| EPG median | 0 (0–5,766) | 522 (0–8,586) |
| EPG geometric mean | 7,564.9 | 6,787.5 |
| EPG arithmetic mean | 7,865.5 | 9,559.8 |
| Minimum EPG | 0 | 0 |
| Maximum EPG | 92,244 | 101.382 |
| Infection intensity | ||
| Light (1–4999 EPG) | 38 (42) | 36 (34) |
| Moderate (5000–49,999 EPG) | 43 (47) | 57 (53) |
| Heavy (≥50,000 EPG) | 10 (11) | 14 (13) |
Data are n (%), median (IQR), mean (SD). EPG = eggs per gram of stool. One child hookworm-negative at baseline excluded from the chewable tablet arm.