Skip to main content
Annals of Gastroenterology logoLink to Annals of Gastroenterology
. 2020 Jun 30;33(6):689. doi: 10.20524/aog.2020.0512

Intraductal simethicone application for optimization of endoscopic view on direct cholangioscopy

Vincent Zimmer a,b,
PMCID: PMC7599346  PMID: 33162749

Direct cholangioscopy (DC) using ultra-slim upper endoscopes has gained wide appreciation for its high-quality visualization of the biliary tract. As opposed to single-operator cholangioscopy, associated with lower visual quality but more technical ease of use, successful DC is dependent on adequate bile duct diameters and a wider-bore papillary access by, for example, maximum-incision papillotomy and/or balloon dilation. This, however, often results in exuberant spontaneous pneumobilia, which, in turn, is notorious for greatly reducing the quality of endoscopic visualization in any gastrointestinal application. Against this background, and despite increasing hygiene concerns related to endoscope re-processing, the utilization of simethicone, a silicone-based polymer, to reduce foam and air bubbles is routine in endoscopy practice; however, it has not been specifically reported for cholangioscopy purposes.

Here we report the case of an elderly female patient undergoing an uncomplicated cholangioscopy-guided electrohydraulic lithotripsy (EHL) under peri-interventional antibiotics using ceftriaxone. Because of her markedly dilated biliary system, neither CO2 nor water instillation was warranted during ultra-slim DC after freehand access in the “J maneuver” technique [1,2]. After reinsertion of the upper endoscope following EHL fragment extractions by conventional endoscopic retrograde cholangiography technology, high-quality cholangioscopic visualization of the hilum was impeded by multiple air bubbles (Fig. 1). After intraductal cleansing with a sterile saline/simethicone mixture applied through a small-sheath catheter, the interference from air bubbles was resolved, allowing full-scale endoscopic assessment of the biliary mucosa (Fig. 2). Notwithstanding that the potential clinical utility of simethicone for improvement of mucosal assessment might be applicable to all endoscopy procedures, this is the first specific report on simethicone use during DC [3].

Figure 1.

Figure 1

High-quality cholangioscopic view of the hilum after freehand intubation of an ultra-slim upper endoscope is impeded by an exuberance of air bubbles

Figure 2.

Figure 2

Extensive intraductal cleansing using a sterile/simethicone mixture applied though a small-sheath catheter provided a full-scale endoscopic visualization of the biliary mucosa

Biography

Marienhausklinik St. Josef Kohlhof, Neunkirchen; Saarland University Medical Center, Homburg, Germany

Footnotes

Conflict of Interest: None

References

  • 1.Brauer BC, Chen YK, Shah RJ. Single-step direct cholangioscopy by freehand intubation using standard endoscopes for diagnosis and therapy of biliary diseases. Am J Gastroenterol. 2012;107:1030–1035. doi: 10.1038/ajg.2012.88. [DOI] [PubMed] [Google Scholar]
  • 2.Zimmer V, Lammert F. Positioning cholangioscopy in bile duct stone management: mind the technology gap. Frontline Gastroenterol. 2018;9:315–316. doi: 10.1136/flgastro-2018-100963. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Devereaux BM, Taylor ACF, Athan E, et al. Simethicone use during gastrointestinal endoscopy: Position statement of the Gastroenterological Society of Australia. J Gastroenterol Hepatol. 2019;34:2086–2089. doi: 10.1111/jgh.14757. [DOI] [PubMed] [Google Scholar]

Articles from Annals of Gastroenterology are provided here courtesy of The Hellenic Society of Gastroenterology

RESOURCES