Table 1.

Indices used to define the diabetic phenotype of a subject.

Index	Formula	Indicator of
Matsuda Index [19]	10000/√(fG × fI)(mG x mI)	Systemic insulin sensitivity
Disposition Index (DI) [20]	[AUC30min insulin/AUC30min glucose] × Matsuda	β-cell function
Hepatic Insulin Resistance Index (HIRI) [18]	fG × fI	Hepatic insulin resistance
Muscle Insulin Sensitivity Index (MISI) [18]	(∆G/∆t)/mI	Muscle insulin resistance
Adipose Tissue Insulin Resistance Index (Adipo-IR) [21]	Fasting FFA × fI	Adipose tissue insulin resistance

Abbreviations used: fG = fasting plasma glucose; fI = fasting plasma insulin; mG = mean plasma glucose; mI = mean plasma insulin; AUC = area under the curve; ∆G = delta glucose; ∆t = delta time; FFA = free fatty acids. Units used: for glucose mg/dL; for insulin U/L; for FFA mmol/L.