Abstract
Objective
To assess the usefulness and safety of flexible bronchoscopy in ventilated neonates with extubation failure.
Method
This was a prospective observational study. Flexible bronchoscopy was done in eligible patients with failure of extubation form invasive ventilation. The main outcome measure was to find the presence of any anatomic or dynamic abnormalities of the airways of these patients and the organism profile of bronchoalveolar lavage (BAL) fluid.
Results
Forty-eight babies (68.8% preterm) were enrolled in the study. The most common finding on bronchoscopy was airway edema seen in 13 (27%) patients. BAL culture was positive in 29 (74%) patients. Overall treatment was modified in 35 (73%) patients based on bronchoscopy findings/BAL culture. Majority of infants (83.3%) tolerated the procedure very well.
Conclusion
Flexible bronchoscopy provides useful information in the management of newborn babies with extubation failure.
Keywords: Bronchoalveolar lavage, Extubation failure, Management, Preterm
Contributors
JIB, BAC: conceived the idea of the study and writing the manuscript; SZ: was involved in management and data collection; QIA: supervised implementation of the study; AAA: contributed to writing of the manuscript. All authors approved the final version of manuscript, and are accountable for all aspects related to the study.
Funding
None
Ethics clearance
Departmental Review Board, SIMS; No. SIMS/152/12/279; dated June 2, 2016.
Footnotes
Competing interest
None stated.
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