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Journal of the American Society of Nephrology : JASN logoLink to Journal of the American Society of Nephrology : JASN
letter
. 2020 Aug 19;31(10):2492–2493. doi: 10.1681/ASN.2020071089

Authors’ Reply

Alan Kliger 1,
PMCID: PMC7609016  PMID: 32999039

We agree that there are limitations to the use of Sequential Organ Failure Assessment (SOFA) scores for stratification of mortality risk of patients with CKD and ESKD.1 Using a single creatinine (or daily urine volume) measurement to assess the kidney function of patients with CKD is one of many limitations of SOFA scores, as is the lack of differentiation in the SOFA score between acute kidney disease and CKD. We agree that these limitations are particularly important when used to compare one individual with another for possible resource prioritization, and acknowledge that the SOFA score, along with virtually all other severity of illness scores, tends to overestimate mortality risk of patients with advanced CKD. Nevertheless, while recognizing these caveats, we believe that the SOFA score is still helpful to objectively assess patients with complex illness, but agree with Dr. Sanghavi2 that even better methods to assess mortality risk are needed to optimize equitable allocation of resources in the setting of scarcity.

Disclosures

The author has nothing to disclose.

Funding

None.

Footnotes

Published online ahead of print. Publication date available at www.jasn.org.

References

  • 1.Silberzweig J, Ikizler TA, Kramer H, Palevsky PM, Vassalotti J, Kliger AS: Rationing scarce resources: The potential impact of COVID-19 on patients with chronic kidney disease. J Am Soc Nephrol 31: 1926–1928, 2020 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Sanghavi S: Critically ill patients with CKD deserve better mortality prediction scores. J Am Soc Nephrol 31: 2492, 2020 [DOI] [PMC free article] [PubMed] [Google Scholar]

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