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. Author manuscript; available in PMC: 2021 May 25.
Published in final edited form as: Nature. 2020 Jul 22;585(7823):85–90. doi: 10.1038/s41586-020-2498-z

Figure 1. Spread of Wingless does not involve multimeric assemblies but requires Dlp.

Figure 1

a) Morphotrap (NRT-MYC-LaG16) driven in the posterior compartment by hh-Gal4 captures GFP-Wingless, but not Wingless-HA (both expressed from knock-in alleles). In the control anterior compartment, both forms of Wingless show a graded distribution. The experiment was repeated independently three times with similar results. b, c) Extracellular Wingless is reduced to a greater extent in clones lacking Dlp than clones lacking Dally (clones marked by the absence of GFP (white arrowheads). Scale bars represent 10μm in a and 25μm in b and c. The experiments were repeated independently three times with similar results.