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. 2020 Nov 4;40(13):1422–1431. doi: 10.1177/0333102420965140

Table 3.

Characteristics of COVID-19 related headache in relation to gender, smoking state, pre-existing primary headache disorder, fever, dehydration, steroids, comorbidities and COVID-19 severity.

Frequency/week, median (IQR) Duration (hours), median (IQR) VAS, median (IQR)
Gender
 Males, n = 64 (37.2%) 3 (2–7) 16 (2–24) 7 (0–10)
 Females, n = 108 (62.8%) 5 (2–7) 12 (2–24) 8 (0–10)
p-value 0.56 0.54 0.51
Smoking state
 Smoker, n = 15 (8.7%) 6 (2–7) 16 (2–24) 7 (4–10)
 Non-smoker, n = 157 (91.2 %) 4 (2–7) 10 (2–24) 5 (0–10)
p-value 0.45 0.36 0.77
Pre-existing primaryheadache*
 With, n = 91 (52.9%) 7 (3–7) 12 (4–16) 7 (5–8)
 Without, n = 81 (47.1%) 3 (2–7) 6 (2–16) 7 (5–8)
p-value <0.001* 0.55 0.34
Fever*
 With, n = 120 (69.8%) 7 (3–7) 11 (4–16) 7 (6–8)
 Without, n = 52 (30.2%) 3 (2–7) 6 (2–16) 6 (4–8)
p-value 0.003* 0.292 0.012*
Dehydration*
 With, n = 111 (64.5%) 7 (3–7) 6 (2–16) 7 (5–8)
 Without, n = 61 (35.5%) 3 (2–7) 6 (2–16) 6 (5–8)
p-value 0.029* 0.506 0.201
Steroids
 Received, n = 54 (31.4%) 7 (3–7) 6 (2–13) 7 (5–8)
 Not received, n = 118 (68.6%) 7 (3–7) 6 (4–16) 7 (5–8)
p-value 0.965 0.295 0.924
Comorbidities
 With, n = 34 (19.8%) 7 (7–7) 12 (2–16) 8 (6–10)
 Without, n = 138 (80.2%) 5 (2–7) 6 (2–16) 6.5 (5–8)
p-value 0.006* 0.235 0.003*
Grading severity of COVID-19 infection
 Mild, n = 116 (67.4%) 3 (2–7) 6 (2–15) 6 (5–8)
 Moderate, n = 42 (24.4%) 7 (3–7) 12 (2–16) 8 (6.75–9)
 Severe, n = 14 (8.1%) 7 (2.75–7) 6 (2–16) 7 (5–8.25)
p-value 0.032* 0.134 0.007*

VAS: visual analogue scale.

Note: Bold p-values < 0.05 are considered significant.

*These groups were matched regarding age, sex, comorbidities and COVID-19 severity.