Dear Editor,
We read the letter to the editor by V. Wiwanitkit with the title “SARS-CoV-2 in semen” [1]. The author emphasizes that even if semen has a very low possibility for transmission of the virus, the disease can be transmitted by the respiratory route due to the very close contact between partners. Actually, we think the same as the author. Transmission with respiratory secretions during sexual contact poses a much greater risk than the transmission through semen [2, 3]. We think that even if severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is detected in a patient's semen sample, it is quite difficult to say that the transmission between partners has solely been through semen. As the risk of transmission with respiratory secretion is clearly defined from the beginning of the pandemic, we did not have a need to emphasize this point. In our study, we only aimed to investigate the role of semen in disease transmission. The risk of respiratory contact or other risky behaviors that are revealed during sexual activity was not mentioned. Our study argues that there is probably no additional transmission risk via semen. The available data also support our study that SARS-CoV-2 is not a sexually transmitted virus [4, 5, 6, 7, 8]. However, sexual contact carries a high risk in terms of SARS-CoV-2 transmission between partners through the respiratory secretions, not semen.
Conflict of Interest Statement
There is no conflict of interest.
Author Contributions
All authors searched the literature and argued the text. Bircan Kayaaslan wrote the letter. All authors read and accepted the final version.
References
- 1.Wiwanitkit V. SARS-CoV-2 in Semen. Manuscript no: UIN-2020-8-67. (THERE WAS NO DOI NUMBER) [Google Scholar]
- 2.World Health Organization Transmission of SARS-CoV-2: implications for infection prevention precautions. 2020 Available at: https://www.who.int/news-room/commentaries/detail/transmission-of-sars-cov-2-implications-for-infection-prevention-precautions. [Google Scholar]
- 3.Liu J, Liao X, Qian S, Yuan J, Wang F, Liu Y, et al. Community Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, Shenzhen, China, 2020. Emerg Infect Dis. 2020 Jun;26((6)):1320–3. doi: 10.3201/eid2606.200239. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 4.Pan F, Xiao X, Guo J, Song Y, Li H, Patel DP, et al. No evidence of severe acute respiratory syndrome-coronavirus 2 in semen of males recovering from coronavirus disease 2019. Fertil Steril. 2020 Jun;113((6)):1135–9. doi: 10.1016/j.fertnstert.2020.04.024. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 5.Li D, Jin M, Bao P, Zhao W, Zhang S. Clinical Characteristics and Results of Semen 21 Tests Among Men with Coronavirus Disease 2019. JAMA Netw Open. 2020 May 1;3((5)):e208292. doi: 10.1001/jamanetworkopen.2020.8292. Published 22 online doi: [DOI] [PMC free article] [PubMed] [Google Scholar]
- 6.Guo L, Zhao S, Li W, Wang Y, Li L, Jiang S, et al. Absence of SARS-CoV-2 in semen of a COVID-19 patient cohort. Andrology. 2020 Jun;:andr.12848. doi: 10.1111/andr.12848. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 7.Kayaaslan B, Korukluoglu G, Hasanoglu I, Kalem AK, Eser F, Akinci E, et al. Investigation of SARS-CoV-2 in Semen of Patients in the Acute Stage of COVID-19 Infection. Urol Int. 2020;104((9-10)):678–83. doi: 10.1159/000510531. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 8.Khalili MA, Leisegang K, Majzoub A, Finelli R, Panner Selvam MK, Henkel R, et al. Male Fertility and the COVID-19 Pandemic: Systematic Review of the Literature. World J Mens Health. 2020 Oct;38((4)):506–20. doi: 10.5534/wjmh.200134. [DOI] [PMC free article] [PubMed] [Google Scholar]