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. 2020 Nov 9;8:e10244. doi: 10.7717/peerj.10244

Figure 6. The influences of loading history and 18α-GA on compressive force-induced changes of mRNA expression of interesting genes in MLO-Y4 osteocyte-like cells.

Figure 6

The mRNA expression of (A) RANKL, (B) OPG, (C) RANKL/OPG, (D) Gja1, (E) Sost, (F) Dmp1, (G) PDNP and (H) OCN of MLO-Y4 osteocyte-like cells in response to the new applied or re-applied continuous compressive force (1 h) with or without 18α-GA treatment (2 h). The values of each replicate are presented as the dots. The results are shown as mean ± standard deviation. ANOVA, analysis of variance; Fisher’s least Significant Difference (LSD) test was performed following the ANOVA test. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.