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. 2008 Nov 24;40(7):351–356. [Article in Spanish] doi: 10.1157/13124128

Efectos de un programa de ejercicio de fuerza/resistencia sobre los factores de riesgo cardiovascular en mujeres posmenopáusicas de bajo riesgo cardiovascular. Estudio CLIDERICA

Effects of a structured exercise programme on cardiovascular risk programmes in post-menopausal women. Cliderica study

Pedro Saucedo Rodrigo a, José Abellán Alemán a,⁎, Purificación Gómez Jara a, Mariano Leal Hernández a, Enrique Ortega Toro a, Juan Carlos Colado Sánchez b, Pilar Sáinz de Baranda Andújar a
PMCID: PMC7659840  PMID: 18620637

Abstract

Objective

To analyse the influence of a physical exercise programme of strength/stamina on cardiovascular risk factors in low-riskpost-menopausal women.

Design

Six-month randomised clinical trial with post-menopausal women.

Setting

Three health centres in the autonomous community of Murcia, Spain.

Participants

Sixty-three post-menopausal women aged 45 to 59 at low cardiovascular risk.

Interventions and main measurements

They were split into 2 groups: a) control: 23 people with no specific intervention, and b) 40 people with an intervention of strength/stamina exercise with protocol for in water and on land. At their initial and final visits, everyone in the 2 groups had anamnesis, physical examination, and general analyses, including Apo A, Apo B, insulin, serum creatinine, creatinine clearance, creatinine in urine, albuminuria, ultrasensitive PCR, and HOMA index.

Results

The insulin levels increased in the control group by 2.02 mU/L and dropped in the experimental group by 0.13 mU/L (P=.021). Atthe start ofthe study, creatinine in the control group was 0.83±0.12 mg/dL; and atthe end, 0.91±0.02 mg/dL. In the intervention group it was 0.84±0.12 mg/dL at the start and 0.90±0.13 mg/dL atthe end (NS). Systolic blood pressure dropped in both groups, with a bigger drop in the exercise group (11.81 vs 0.17 mm Hg) (P=.0001). HDL-C values increased in the control group by 4.97 mg/dL; and in the experimental group, by 3.46 mg/dL (NS).

Conclusions

A controlled programme of strength/stamina physical exercise reduces the cardiovascular risk of post-menopausal women.

Key words: Exercise, Post-menopause, Programme, Cardiovascular risk

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