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. 2020 Nov 4;25(21):5134. doi: 10.3390/molecules25215134

Figure 7.

Figure 7

Potential T-stacking interactions between the coumarin ring of studied compounds (SAHA, 7c, 7e, 7f, 7i and 7j center) and the phenylalanine residue (structure in blue labeled as F620) in the active site of HDAC6. T-stacking interactions are displayed as red lines, distances between interacting aromatic moieties are showed in Ångstroms (Å). Zn atom is presented as a pink sphere.