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. 2013 Apr 3;32(1):6–12. [Article in Spanish] doi: 10.1016/S0212-6567(03)78851-9

Detección del deterioro cognitivo en población mayor de 64 años: primera fase del proyecto Cuida’l

Reliability and validity of the spanish version of the mos-sf-30 to assess the health related quality of life in people infected by hiv

E Limón Ramírez 1,*, JM Argimon Pallàs 1, J Vila Doménech 1, T Abos Pueyo 1, C Cabezas Peña 1, E Vinyoles Bargalló 1
PMCID: PMC7669073  PMID: 12812684

Abstract

Objective

To know the proportion of people with positive result in test

Design

Cross sectional study in 53 health centers

Setting

Primary care

Participants

Aleatory sample of noninstitutionalised, elder than 64 years patients attended in the 53 health centers

Measurements

Variables: age, sex, civil status, and educational level. The detection of cognitive deterioration (CD) was carried out in primary care units with Folstein’s Mini Mental Test (MMT) and the Isaacs Set-Test in case of illiteracy. Cut-off points 24 and 27 respectively. CD predictor variables analysis with logistic regression

Main Results

The tests were applied to 4,467 individuals (56.1% females). There were found as possible cases of CD 399 patients (72.2% with MMSE). Positive percentage was 7.78% (95% CI, 5.69%–10.99%) in males and 9.45% (95% CI, 7.31%–12.43%) in female, adjusting with indirect method, according to the 1996 Catalonia list of inhabitants. Significant predictor factors were found with the multivariate analyses: primary educational level in front of illiteracy (OR=1.40, 95% CI, 1.13%–1.74%) and age–groups: 74–79 years, 75–79 years and y > 80 years in front of <70 years old (OR=1,48, 95% CI, 1.02%–2.14%, OR=2.29; 95% CI, 1.60%–3.28% and OR=5,02; 95% CI, 3.59%–7.03% respectively)

Conclusions

The cognitive deterioration prevalence increases with age and it is less frequent in individuals with higher studies Using MMSE and Set-Test we found several possible cases of cognitive deterioration in our population

Keywords: Prediction, Screening, Cognitive deterioration, Dementia

El estudio ha sido parcialmente financiado por la Fundació Marató de TV3 (1019/97), y una versión reducida de éste fue presentada en el Congreso de la semFYC celebrado en Gijón en noviembre de 2000

Bibliografía

  • 1.Folstein M.F., Folstein S.E., McHugh P.R. »Mini-Mental State«: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189–198. doi: 10.1016/0022-3956(75)90026-6. [DOI] [PubMed] [Google Scholar]
  • 2.Escribano-Aparicio M.V., Pérez-Dively M., García-García F.J., Pérez-Martín A., Romero L., Ferrer G. Validación del MMSE de Folstein en una población española de bajo nivel educativo. Rev Esp Geriatr Gerontol. 1999;34:319–326. [Google Scholar]
  • 3.Bermejo F., Morales J.M., Valerga C., del Ser T., Artolazábal J., Gabriel R. Comparación entre dos versiones españolas abreviadas de evaluación del estado mental en el diagnóstico de demencia. Datos de un estudio en ancianos residentes en la comunidad. Med Clin (Barc) 1999;112:330–334. [PubMed] [Google Scholar]
  • 4.McKhann G., Drachman D., Folstein M., Katzman R., Price D., Standlar E.M. Clinical diagnosis of Alzheimer’s disease. Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human services task force on Alzheimer's disease. Neurology. 1984;34:939–944. doi: 10.1212/wnl.34.7.939. [DOI] [PubMed] [Google Scholar]
  • 5.Vinyoles E., Copetti S., Cabezas C., Megido M.J., Espinàs J., Vila J. Aspectos metodológicos de un ensayo clínico que evaluará la eficacia de una intervención en cuidadores de pacientes demenciados. Aten Primaria. 2001;27:49–53. doi: 10.1016/S0212-6567(01)78773-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 6.Bland J.M., Kerry S. Statistic notes: Sample size in cluster randomisation. Bmj. 1998;316:549. doi: 10.1136/bmj.316.7130.549. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 7.Pascual L.F., Martínez J.V., Modrego P., Mostadero E., López del Val J., Morales F. El set-test en el diagnóstico de la demencia. Neurología. 1990;5:16–21. [PubMed] [Google Scholar]
  • 8.http://www.idescat.es
  • 9.Pi J., Olivé J.M., Roca J., Masana L. Prevalence of dementia in a semi-rural population of Catalunya, Spain. Neuroepidemiology. 1996;15:33–41. doi: 10.1159/000109887. [DOI] [PubMed] [Google Scholar]
  • 10.Bermejo F.P., Gabriel R.S., Vega S., Morales J.M., Rocca W.M. Problems and isues with door-to-door, two phase surveys: an ilustration from central Spain. Neuroepidemiology. 2001;20:225–231. doi: 10.1159/000054794. [DOI] [PubMed] [Google Scholar]
  • 11.Jorm A.F., Korten A.E., Henderson A.S. The prevalence of dementia: a quantitative integration of the literature. Acta Psychiatr Scand. 1987;76:465–479. doi: 10.1111/j.1600-0447.1987.tb02906.x. [DOI] [PubMed] [Google Scholar]
  • 12.Ritchie K., Kildea D. Is senile dementia »age-related« or »ageingrelated«? Evidence from meta-analysis of dementia prevalence in the oldest old. Lancet. 1995;346:931–934. doi: 10.1016/s0140-6736(95)91556-7. [DOI] [PubMed] [Google Scholar]
  • 13.Manubens J.M., Martínez-Lage J.M., Lacruz F., Muruzábal J., Larumbe R,Guarch C. Prevalence of Alzheimer’s disease and other dementing disorders in Pamplona, Spain. Neuroepidemiology. 1995;14:155–164. doi: 10.1159/000109791. [DOI] [PubMed] [Google Scholar]
  • 14.Seshadri S., Wolf P.A., Beiser A., Au R., McNulty K., White R. Lifetime risk of dementia and Alzheimer’s disease. The impact of mortality on risks estimates in the Framingham study. Neurology. 1997;49:1498–1504. doi: 10.1212/wnl.49.6.1498. [DOI] [PubMed] [Google Scholar]
  • 15.Puig X., Gispert R., Puigdefábregas A., Pérez G., Mompart A., Doménech J. Mortalidad por demencia en Cataluña: un problema de salud emergente. Med Clin (Barc) 2002;118:455–459. doi: 10.1016/s0025-7753(02)72418-4. [DOI] [PubMed] [Google Scholar]
  • 16.Letteneur L., Launer L.J., Andersen K., Dewey M.E., Ott A., Copeland J.R.M. Education and the risk for Alzheimer’s disease: sex makes a difference. Am J Epidemiol. 2000;151:1064–1071. doi: 10.1093/oxfordjournals.aje.a010149. [DOI] [PubMed] [Google Scholar]
  • 17.Martínez Lage J.M., Martínez Lage P. Educación, reserva cerebral y factores de riesgo de demencia y enfermedad de Alzheimer. Med Clin (Barc) 2001;116:418–421. doi: 10.1016/s0025-7753(01)71853-2. [DOI] [PubMed] [Google Scholar]
  • 18.Del Ser T., Hachinski V., Merskey H., Muñoz D.G. An autopsyverified study of the effect of education on degenerative dementia. Brain. 1999;122:2309–2319. doi: 10.1093/brain/122.12.2309. [DOI] [PubMed] [Google Scholar]
  • 19.Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Lancet. 2001;357:169–175. doi: 10.1016/s0140-6736(00)03589-3. [DOI] [PubMed] [Google Scholar]
  • 20.Muñoz D.G., Ganaphathy G.R., Eliasziw M., Hachinski V. Educational attainment and socioeconomic status of patients with autopsy-confirmed Alzheimer disease. Arch Neurol. 2000;57:85–89. doi: 10.1001/archneur.57.1.85. [DOI] [PubMed] [Google Scholar]
  • 21.Ritchie K., Artero S., Touchon J. Classification criteria for mild cognitive impairment. A population-based validation study. Neurology. 2001;56:37–42. doi: 10.1212/wnl.56.1.37. [DOI] [PubMed] [Google Scholar]
  • 22.García F.J., Sánchez M.I., Pérez A., Martín E., Marsal C., Rodríguez G. Prevalencia de demencia y de sus subtipos principales en sujetos mayores de 65 años: efecto de la educación y ocupación. Estudio Toledo. Med Clin (Barc) 2001;116:401–407. doi: 10.1016/s0025-7753(01)71849-0. [DOI] [PubMed] [Google Scholar]
  • 23.Helmer C., Damon D., Letenneur L., Fabrigoule C., Barberger-Gateau P., Lafont S. Marital status and risk of Alzheimer’s disease. A French population-based cohort study. Neurology. 1999;53:1953–1958. doi: 10.1212/wnl.53.9.1953. [DOI] [PubMed] [Google Scholar]
  • 24.Fratiglioni L., Wang H.X., Ericsson K., Maytan M., Winblad B. Influence of social network on ocurrence of dementia: a community-based longitudinal study. Lancet. 2000;355:1315–1319. doi: 10.1016/S0140-6736(00)02113-9. [DOI] [PubMed] [Google Scholar]
  • 25.López-pousa S., Llinás J., Vilalata J., Lozano L. Prevalencia de las demencias en Girona. Neurología. 1995;10:189–193. [Google Scholar]
  • 26.Boada M. Trastornos cognitivos en la población geriátrica de la ciudad de Barcelona: aproximación clínicoepidemiológica (tesis doctoral) Universitat de Barcelona; Barcelona: 1993. [Google Scholar]
  • 27.González M.J., Escrivà R., Vinyoles E., Espel C., Davins J., Borrell M. Estimaciones de la frecuencia de déficit cognitivo según el test empleado. Aten Primaria. 1997;20:173–179. [PubMed] [Google Scholar]
  • 28.Pérez J.M., Tiberio G. Deterioro cognitivo y demencias en una población geriátrica urbana. Aten Primaria. 1992;9:365–369. [PubMed] [Google Scholar]
  • 29.Vilalta-Franch J., López-pousa S., Llinàs-reglà J. Prevalencia de demencias en una zona rural. Estudio de Girona. Rev Neurol. 2000;30:1026–1032. [PubMed] [Google Scholar]
  • 30.Lobo A., Saz P., Marcos G., Dia J.L., de la Camara C. The Prevalence of Dementia and Depression in the Elderly Community in a Southern European Population: The Zaragoza Study. Arch of Gen Psychiatr. 1995;52:497–506. doi: 10.1001/archpsyc.1995.03950180083011. [DOI] [PubMed] [Google Scholar]

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