Table 3.

Marginal effect (Absolute least square (LS) mean difference) of CBT compared to HL on percent drinking days and drinks per drinking day averaged over the entire study and across three study phases. Sensitivity analyses for these results

Absolute least squares mean differences					Sensitivity analyses*
Percent Drinking Days
	Estimate (std. error)				Estimate (std. error)
Study Period	CBT	HL	LS mean diff (95%CI)	p-value	CBT	HL	LS mean diff (95%CI)	p-value
Overall	7.58 (0.678)	10.26 (0.695)	2.68 (0.77, 4.58)	0.0059	10.20 (0.876)	13.63 (0.896)	−3.42(−5.88, −0.97)	0.0063
Intervention (baseline-6wks)	21.14 (0.978)	25.33 (1.001)	5.20 (2.45, 7.94)	<0.001	22.40 (1.025)	27.62 (1.049)	−5.22(−8.10, −2.34)	0.0004
Follow up (7-30 wks)	5.35 (0.748)	8.11 (0.767)	2.76 (0.65, 4.86)	0.0102	7.46 (0.897)	10.81 (0.917)	−3.35(−5.87, −0.83)	0.0091
Maintenance (31-46 wks)	3.64 (0.696)	5.72 (0.712)	2.08 (0.13, 4.04)	0.037	9.17 (1.167)	11.55 (1.193)	−2.38(−5.62, 0.86)	0.1496
Drinks per Drinking Day
	Estimate (std. error)				Estimate (std. error)
Study Period	CBT	HL	LS mean difld> (95%CI)	p-value	CBTld>	HLd>	LS mean diff (95%CI)	p-value
Overall	1.15 (0.091)	1.69 (0.093)	0.55 (0.29, 0.80)	<.0001	1.47 (0.116)	2.00 (0.119)	−0.53(−0.85, −0.20)	0.0015
Intervention (baseline-6wks)	2.69 (0.128)	3.47 (0.131)	0.78 (0.42, 1.14)	<.0001	2.98 (0.136)	3.75 (0.139)	−0.77(−1.15, −0.39)	<0.0001
Follow up (7-30 wks)	0.83 (0.103)	1.51 (0.106)	0.67 (0.38, 0.96)	<.0001	1.16 (0.126)	1.79 (0.129)	−0.64(−0.99, −0.28)	0.0004
Maintenance (31-46 wks)	0.66(0.096)	0.98 (0.098)	0.31 (0.05, 0.58)	0.0218	1.29 (0.141)	1.55 (0.144)	−0.25(−0.65, 0.14)	0.2082

^*Sensitivity analyses assumed that those who were lost-to-follow-up had returned to baseline drinking levels