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. 2020 Sep 18;70(3):593–606. doi: 10.1007/s12020-020-02478-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Serum pituitary hormone levels and vessel parameters in PitNETs. a Correlation between serum IGF-1 levels and vessel perimeter within the whole cohort of PitNETs. b Correlation between serum IGF-1 levels and Feret’s diameter within the whole cohort of PitNETs. c Correlation between serum IGF-1 levels and vessel perimeter within NF-PitNETs. d Correlation between serum IGF-1 and vessel perimeter within somatotrophinomas. e Correlation between serum-free FT4 levels and MVD within somatotrophinomas. P values were determined by the Spearman’s correlation coefficient rho. FT4 free thyroxine, HPF high-power field, IGF-1 insulin-like growth factor 1, MVD microvessel density, NF-PitNET non-functioning pituitary neuroendocrine tumour, PitNET pituitary neuroendocrine tumour