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. 2020 Nov 13;23(1):12–20. doi: 10.1016/j.neo.2020.11.001

Figure 2.

Figure 2

Survival curves illustrate the influence of the CNL genomic background over the impact of MYCN status over survival. (A and B) OS and EFS of HR-NB patients without any stratification (C and D) The impact of MYCN status on the OS of HR-NB patients depends on the CNL genomic subtype. (C) Patients with nCNL tumors and homMNA have a markedly low OS in comparison to patients with non-MNA and hetMNA, while no difference is observed for the different MYCN status in the OS of patients with pCNL tumors (D). CNL, copy number load; hetMNA, heterogeneous MYCN amplification; homMNA, homogeneous MYCN amplification; MNA, MYCN amplification; nCNL, negative copy number load; OS, overall survival; pCNL, positive copy number load.