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. 2013 Apr 5;25(3):148–152. [Article in Spanish] doi: 10.1016/S0212-6567(00)78478-2

Brote epidémico de parotiditis. Estudio de la efectividad vacunal

Epidemic Outbreak of Mumps: Study of The Effectiveness of Vaccination

B López Hernández a,b,1,*, RM Martín Vélez b,1, C Román García b,1, I Peñalver Sánchez c,1,1, JA López Rosique b,d,1
PMCID: PMC7675796  PMID: 10730437

Abstract

Objective

Description of an outbreak of mumps in an urban area. Study of the effectiveness of the mumps component of the triple virus (TV) vaccination.

Design

Cross sectional descriptive study of the outbreak. The cases were obtained from the Andalusian Register of Infectious Diseases (SVEA in Spanish). The effectiveness of the vaccine was studied through a retrospective cohort design, with the cohorts defined according to their vaccination history.

Setting

Urban area of low social class and income and young population pyramid. The outbreak occurred between March and November 1997. The effectiveness of vaccination at one school was studied.

Patients and other participants

Residents in the area. The source of the population was the 1996 municipal census.

Interventions

The declared cases of mumps were taken from the SVEA. The state of vaccination was documented through a review of the school registration records, vaccination cards and the health centre register of names.

Measurements and main results

A total of 283 cases of mumps were declared. There were more cases in the 0-10 age group than at older ages. 79% of cases were vaccinated (95% CI, 74.3-73.7). Effectiveness of a dose of the mumps component of the vaccine was low (46%; CI, 0-84), though the effectiveness of a second dose was higher (87%; CI, 27-99).

Conclusions

The low effectiveness of the mumps component of the TV vaccination was confirmed. It is proposed that the age for the second dose should be brought forward to schoolstarting age (primary, first year). Ensuring school vaccination is recommended.

Key words: Mumps, Epidemic outbreak, Vaccine effectiveness

Bibliografía

  • 1.Comité Asesor de Vacunas. Asociación Española de Pediatría. Vacunaciones sistemáticas. En: Manual de vacunas en Pediatría. Edición Andalucía, 1998 [Google Scholar]
  • 2.Dirección General de Salud Pública. Ministerio de Sanidad y Consumo. Cobertura vacunal 1997. Boletín Epidemiológico Semanal. 1998;6(21):197–208. [Google Scholar]
  • 3.Pachón I., Tormo A. Situación de la parotiditis en España durante 1996. Boletín Epidemiológico Semanal. 1997;5:13–20. [Google Scholar]
  • 4.Unidad de Vigilancia Epidemiológica. Gerencia Provincial. Enfermedades de declaración obligatoria. Granada 1992 Enfermedades de alta incidencia. Primera parte. Boletín Epidemiológico Provincial de Granada. 1993;12(1):1–4. [Google Scholar]
  • 5.Sección de Epidemiología. Delegación Provincial de Salud. Incidencia de EDO en Granada. Año 1997 (1.a parte) Boletín Epidemiológico Provincial de Granada. 1998;17(2):1–4. [Google Scholar]
  • 6.Dirección General de Salud Pública y participación. Consejería de Salud. Junta de Andalucía. Parotiditis. Informe Semanal SVEA. 1997;2(47) [Google Scholar]
  • 7.Consejería de Sanidad de Castilla La Mancha. CSBS; Toledo:: 1991. Etapas en el estudio de un brote epidémico. En: Consejería de Sanidad y Bienestar Social, editores. Procedimientos para la investigación de brotes epidémicos; pp. 11–43. [Google Scholar]
  • 8.Centro Nacional de Epidemiología. Ministerio de Sanidad y Consumo; Madrid:: 1996. Protocolos de las enfermedades de declaración obligatoria. [Google Scholar]
  • 9.Orestein W.A., Bernier R.M., Dondero T.J., Hinman A.R., Marks J.S., Bart K.J. Field evaluation of vaccine efficacy. Bull WHO. 1985;63:1055–1068. [PMC free article] [PubMed] [Google Scholar]
  • 10.Guimbao J., Moreno M.P., Gutiérrez V., Pac M.R., Arribas F. La parotiditis en época posvacunal. Patrón epidemiológico y efectividad vacunal en un brote epidémico. Med Clin (Barc) 1992;99:281–285. [PubMed] [Google Scholar]
  • 11.Fernández de la Hoz K., García Colmenro C., Puchades M.J., Verde C., Carpintero J.L., Alcázar F. Epidemia de parotiditis en el área sanitaria de Toledo con intervención mediante inmunización. Estimación de la efectividad de la vacuna. Med Clin (Barc) 1997;108:175–179. [PubMed] [Google Scholar]
  • 12.Sandra J.M., Herrero B., Lozano M.C. Brote de parotiditis en la provincia de Ávila. Año 1995. Boletín Epidemiológico Semanal. 1995;3(9):113–120. [Google Scholar]
  • 13.Black F.L. Measles and mumps. In: Noel R., Conway E., Folds J.D., Lane H.C., Nakamura R.M., editors. Manual of clinical laboratory inmunology. ASM Press; Washington:: 1997. pp. 688–691. [Google Scholar]
  • 14.Pisón F.J., Galbe J., Arcauz P., Aguirre C., Mengual J., Larrad L. Inmunidad frente a sarampión, rubéola y parotiditis en niños vacunados con la triple viral. Aten Primaria. 1995;15:235–237. [PubMed] [Google Scholar]
  • 15.Dias J.A., Cordeiro M., Afzal M.A., Freitas M.G., Morgado M.R., Silva J.L. Mumps epidemic in Portugal despite high vaccine coverage - preliminary report. Eurosurveillance. 1996;1:25–28. doi: 10.2807/esm.01.04.00160-en. [DOI] [PubMed] [Google Scholar]
  • 16.The Benevento and Compobasso Pediatricians Network for the Control of Vaccine- Preventable. Field evaluation of the clinical effectiveness of vaccines against pertussis, measles, rubella and mumps. Vaccine. 1998;16:818–822. doi: 10.1016/s0264-410x(97)00270-3. [DOI] [PubMed] [Google Scholar]
  • 17.Germann D., Strohle A., Eggenberger K., Steinr C.A., Matter L. An outbreak of mumps in a population partially vaccinated with the Rubini strain. Scand J Infect Dis. 1996;28:235–238. doi: 10.3109/00365549609027163. [DOI] [PubMed] [Google Scholar]
  • 18.Chamot E., Toscani L., Egger P., Germann D., Bourquin C. Estimation de l'efficacité de trois souches vaccinales ourliennes au cours d'une épidémie d'oreillons dans le canton de Genéve (Suisse) Rev Epidémiol Sante Publique. 1998;46:100–107. [PubMed] [Google Scholar]
  • 19.Gay N., Miller E., Hesketh L., Morgan-Capner P. Mumps surveillance in England and Wales supports introduction of two dose vaccination schedule. Commun Dis Rep CDR Rev. 1997;7:21–26. [PubMed] [Google Scholar]
  • 20.Peltota H., Heinonen O.P., Valle M., Paunio M., Virtanen M., Karanko V. The elimination of indigenous measles, mumps, and rubella from Finland by a 12-year, two-dose vaccination program. N Engl J Med. 1994;331(21):1397–1401. doi: 10.1056/NEJM199411243312101. [DOI] [PubMed] [Google Scholar]
  • 21.Cheek J.E., Baron R., Atlas H., Wilson D.L., Crider R.D., Jr. Mumps outbreak in a highly vaccinated school population. Evidence for large-scale vaccination failure. Arch Pediat Adol Med. 1995;149:774–778. doi: 10.1001/archpedi.1995.02170200064010. [DOI] [PubMed] [Google Scholar]
  • 22.Johnson H., Hillary I.B., McQuoid G., Gilmer B.A. MMR vaccination, measles epidemiology and sero-surveillance in the Republic of Ireland. Vaccine. 1995;13:533–537. doi: 10.1016/0264-410x(94)00021-e. [DOI] [PubMed] [Google Scholar]
  • 23.Pachón I., Amela C., Ory F., León P., Alonso M. Encuesta nacional de seroprevalencia de enfermedades inmunoprevenibles. Año 1996. Boletín Epidemiológico Semanal. 1998;6(10):93–104. [Google Scholar]
  • 24.Gallardo V., Camino F., García J., Escalera M.A., Sánchez J.J., Cabrera A. Consejería de Salud; Sevilla:: 1999. Encuesta seroepidemiológica de Andalucía. Junta de Andalucía. [Google Scholar]

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