Table 6. Molecular docking analysis results of the ligands and receptor with participating aa residues (3.5 Å).
| Category | AA involved | Aromatic AA | Hydrophobic AA | AA-H-bonds |
|---|---|---|---|---|
| microRNA-hAgo2 | 40a | PHE156 | LEU265 | SER828 |
| TYR174 | ILE353 | GLU821 | ||
| THR357 | VAL237 | THR830 | ||
| TYR225 | LEU238 | ASP823 | ||
| VAL256 | LYS550 | |||
| ILE353 | ASP499 | |||
| LEU356 | HIS829 | |||
| ALA603 | ||||
| ALA825 | ||||
| Duplex-hAgo2 | 59a | PHE156 | ILE159 | ARG69 |
| THR526 | ILE353 | ARG287 | ||
| THR285 | VAL206 | GLU826 | ||
| TYR338 | VAL284 | ARG286 | ||
| ALA825 | ASP252 | |||
| LYS65 | ||||
| SER828 | ||||
| SER824 | ||||
| GLU821 | ||||
| GLU821 | ||||
| PRO523 |
AA; amino acid. Total hydrophobic residual amino acid involved in docking interaction.