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. 2013 Apr 5;31(7):453–457. [Article in Spanish] doi: 10.1016/S0212-6567(03)79206-3

Vacunas combinadas (I)

J Puig-Barberà a,*, J Díez Domingo b
PMCID: PMC7679706  PMID: 12735889

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Bibliografía

  • 1.Madlon-Kay D.J., Harper P.G. Too many shots? Parent, nurse, and physician attitudes toward multiple simultaneous childhood vaccinations. Arch Fam Med. 1994;3:610–613. doi: 10.1001/archfami.3.7.610. [DOI] [PubMed] [Google Scholar]
  • 2.Holt E., Guyer B., Hughart N., Keane V., Vivier P., Ross A. The contribution of missed opportunities to childhood underimmunization in Baltimore. Pediatrics. 1996;97:474–480. [PubMed] [Google Scholar]
  • 3.Combination vaccines for childhood immunization MMWR Recomm Rep. 1999;48:1–14. [PubMed] [Google Scholar]
  • 4.Combined vaccines simultaneous administration: current issues perspectives. Conference proceedings. Ann N Y Acad Sci. 1995;754:xi–404. Bethesda, Maryland, July 28–30, [PubMed] [Google Scholar]
  • 5.Brown K.R. Industry perspective on clinical trial issues for combination vaccines. Ann N Y Acad Sci. 1995;754:241–249. doi: 10.1111/j.1749-6632.1995.tb44456.x. [DOI] [PubMed] [Google Scholar]
  • 6.Postema A.S., Myers M.G., Breiman R.F. Challenges in the development, licensure, and use of combination vaccines. Clin Infect Dis. 2001;33(Suppl 4):S261–266. doi: 10.1086/322560. [DOI] [PubMed] [Google Scholar]
  • 7.Yeh S.H., Ward J.I. Strategies for development of combination vaccines. Pediatr Infect Dis J. 2001;20:S5–9. doi: 10.1097/00006454-200111001-00001. [DOI] [PubMed] [Google Scholar]
  • 8.Decker M.D., Edwards K.M. Combination vaccines. In: Plotkin S.A., Orenstein W.A., editors. Vaccines. W.B. Saunders Company; Philadelphia: 1999. pp. 508–530. [Google Scholar]
  • 9.Dal Re R. Las vacunas combinadas de administracion parenteral en el calendario de vacunaciones sistematicas. Med Clin (Barc) 2000;114:264–270. doi: 10.1016/s0025-7753(00)71265-6. [DOI] [PubMed] [Google Scholar]
  • 10.Insel R.A. Potential alterations in immunogenicity by combining or simultaneously administering vaccine components. Ann N Y Acad Sci. 1995;754:35–47. doi: 10.1111/j.1749-6632.1995.tb44436.x. [DOI] [PubMed] [Google Scholar]
  • 11.Halsey N.A. Safety of combination vaccines: perception versus reality. Pediatr Infect Dis J. 2001;20:S40–44. doi: 10.1097/00006454-200111001-00007. [DOI] [PubMed] [Google Scholar]
  • 12.Dagan R., Eskola J., Leclerc C., Leroy O. Reduced response to multiple vaccines sharing common protein epitopes that are administered simultaneously to infants. Infect Immun. 1998;66:2093–2098. doi: 10.1128/iai.66.5.2093-2098.1998. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13.White C.J., Stinson D., Staehle B., Cho I., Matthews H., Ngai A. Measles, mumps, rubella, and varicella combination vaccine: safety and immunogenicity alone and in combination with other vaccines given to children. Measles, Mumps, Rubella, Varicella Vaccine Study Group. Clin Infect Dis. 1997;24:925–931. doi: 10.1093/clinids/24.5.925. [DOI] [PubMed] [Google Scholar]
  • 14.Granoff D.M., Rappuoli R. Are serological responses to acellular pertussis antigens sufficient criteria to ensure that new combination vaccines are effective for prevention of disease? Dev Biol Stand. 1997;89:379–389. [PubMed] [Google Scholar]
  • 15.Granoff D.M. Challenges for licensure of new diphtheria, tetanus, acellular pertussis (DTaP) combination vaccines: point. Pediatr Infect Dis J. 1996;15:1069–1070. doi: 10.1097/00006454-199612000-00002. [DOI] [PubMed] [Google Scholar]
  • 16.Granoff D.M. Assessing efficacy of Haemophilus influenzae type b combination vaccines. Clin Infect Dis. 2001;33(Suppl 4):S278–S287. doi: 10.1086/322563. [DOI] [PubMed] [Google Scholar]
  • 17.Eskola J., Ward J., Dagan R., Goldblatt D., Zepp F., Siegrist C.A. Combined vaccination of Haemophilus influenzae type b conjugate and diphtheria-tetanus-pertussis containing acellular pertussis. Lancet. 1999;354:2063–2068. doi: 10.1016/S0140-6736(99)04377-9. [DOI] [PubMed] [Google Scholar]
  • 18.Dagan R., Igbaria K., Piglansky L., Melamed R., Willems P., Grossi A. Safety and immunogenicity of a combined pentava-lent diphtheria, tetanus, acellular pertussis, inactivated poliovirus and Haemophilus influenzae type b-tetanus conjugate vaccine in infants, compared with a whole cell pertussis pentavalent vaccine. Pediatr Infect Dis J. 1997;16:1113–1121. doi: 10.1097/00006454-199712000-00004. [DOI] [PubMed] [Google Scholar]
  • 19.Aristegui J., Dal Re R., Garrote E., Gonzalez A., Arrate J.P., Perez A. Assessment of the immunogenicity and reactogenicity of a quadrivalent diphtheria, tetanus, acellular pertussis and hepatitis B (DTPa-HBV) vaccine administered in a single injection with Haemophilus influenzae type b conjugate vaccine, to infants at 2, 4 and 6 months of age. Vaccine. 1998;16:1976–1981. doi: 10.1016/s0264-410x(98)00114-5. [DOI] [PubMed] [Google Scholar]
  • 20.Zepp F., Schmitt H.J., Kaufhold A., Schuind A., Knuf M., Habermehl P. Evidence for induction of polysaccharide specific B-cell-memory in the 1st year of life: plain Haemophilus influenzae type b-PRP (Hib) boosters children primed with a tetanus-conjugate Hib-DTPa-HBV combined vaccine. Eur J Pediatr. 1997;156:18–24. doi: 10.1007/s004310050544. [DOI] [PubMed] [Google Scholar]
  • 21.Pichichero M.E., Passador S. Administration of combined diphtheria and tetanus toxoids and pertussis vaccine, hepatitis B vaccine, and Haemophilus influenzae type b (Hib) vaccine to infants and response to a booster dose of Hib conjugate vaccine. Clin Infect Dis. 1997;25:1378–1384. doi: 10.1086/516154. [DOI] [PubMed] [Google Scholar]
  • 22.Schmitt H.J., von Kries R., Hassenpflug B., Hermann M., Siedler A., Niessing W. Haemophilus influenzae type b disease: impact and effectiveness of diphtheria-tetanus toxoids-acellular pertussis (-inactivated poliovirus)/H. influenzae type b combination vaccines. Pediatr Infect Dis J. 2001;20:767–774. doi: 10.1097/00006454-200108000-00010. [DOI] [PubMed] [Google Scholar]
  • 23.Greco D., Salmaso S., Mastrantonio P., Giuliano M., Tozzi A.E., Anemona A. A controlled trial of two acellular vaccines and one whole-cell vaccine against pertussis. Progetto Pertosse Working Group. N Engl J Med. 1996;334:341–348. doi: 10.1056/NEJM199602083340601. [DOI] [PubMed] [Google Scholar]
  • 24.Calbo F., Dal Re R., Díez-Delgado J., Ona S., Sánchez-Prados F., García-Corbeira P. Comparative trial to assess the reactogenicity of the diphtheria-tetanus-acellular pertussis (DTPa) vaccine plus Haemophilus influenzae type b (Hib) conjugate vaccine and that of the diphtheria-tetanus-whole cell pertussis (DTPw) vaccine plus Hib conjugate vaccine, administered in single injection a. Med Clin (Barc) 2002;118:1–4. doi: 10.1016/s0025-7753(02)72265-3. [DOI] [PubMed] [Google Scholar]
  • 25.Gustafsson L., Hallander H.O., Olin P., Reizenstein E., Storsaeter J. A controlled trial of a two-component acellular, a five-component acellular, and a whole-cell pertussis vaccine. N Engl J Med. 1996;334:349–355. doi: 10.1056/NEJM199602083340602. [DOI] [PubMed] [Google Scholar]
  • 26.Galil K., Singleton R., Levine O.S., Fitzgerald M.A., Bulkow L., Getty M. Reemergence of invasive Haemophilus influenzae type b disease in a well-vaccinated population in remote Alaska. J Infect Dis. 1999;179:101–106. doi: 10.1086/314569. [DOI] [PubMed] [Google Scholar]
  • 27.Pichichero M.E., Latiolais T., Bernstein D.I., Hosbach P., Christian E., Vidor E. Vaccine antigen interactions after a combination diphtheria-tetanus toxoid-acellular pertussis/purified capsular polysaccharide of Haemophilus influenzae type b-tetanus toxoid vaccine in two-, four- and six-month-old infants. Pediatr Infect Dis J. 1997;16:863–870. doi: 10.1097/00006454-199709000-00009. [DOI] [PubMed] [Google Scholar]
  • 28.Halsey N.A., Blatter M., Bader G., Thoms M.L., Willingham F.F., O’Donovan J.C. Inactivated poliovirus vaccine alone or sequential inactivated and oral poliovirus vaccine in two-,four-and six-old infabts with combination Haemophilus influenzae Type b/hepatitis B vaccine. Pediatr Infect Dis J. 1997;16:675–679. doi: 10.1097/00006454-199707000-00010. [DOI] [PubMed] [Google Scholar]
  • 29.Wakefield A.J., Murch S.H., Anthony A., Linnell J., Casson D.M., Malik M. Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet. 1998;351:637–641. doi: 10.1016/s0140-6736(97)11096-0. [DOI] [PubMed] [Google Scholar]
  • 30.Taylor B., Miller E., Farrington C.P., Petropoulos M.C., Favot-Mayaud I., Li J. Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association. Lancet. 1999;353:2026–2029. doi: 10.1016/s0140-6736(99)01239-8. [DOI] [PubMed] [Google Scholar]
  • 31.Halsey N.A., Hyman S.L. Measles-mumps-rubella vaccine and autistic spectrum disorder: report from the New Challenges in Childhood Immunizations Conference convened in Oak Brook, Illinois, June 12–13, 2000. Pediatrics. 2001;107:E84. doi: 10.1542/peds.107.5.e84. [DOI] [PubMed] [Google Scholar]
  • 32.Kaye J.A., Mar Melero-Montes M., Jick H. Mumps, measles, and rubella vaccine and the incidence of autism recorded by general practitioners: a time trend analysis. BMJ. 2001;322:460–463. doi: 10.1136/bmj.322.7284.460. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 33.Shaheen S.O., Aaby P., Hall A.J., Barker D.J., Heyes C.B., Shiell A.W. Measles and atopy in Guinea-Bissau. Lancet. 1996;347:1792–1796. doi: 10.1016/s0140-6736(96)91617-7. [DOI] [PubMed] [Google Scholar]
  • 34.Offit P.A., Quarles J., Gerber M.A., Hackett C.J., Marcuse E.K., Kollman T.R. Addressing parents’ concerns: do multiple vaccines overwhelm or weaken the infant’s immune system? Pediatrics. 2002;109:124–129. doi: 10.1542/peds.109.1.124. [DOI] [PubMed] [Google Scholar]
  • 35.Oostvogel P.M., Rumke H.C., Conyn-van Spaendonck M.A., van der Avoort H.G., Leeuwenburg J., van Loon A.M. Poliovirus circulation among schoolchildren during the early phase of the 1992–1993 poliomyelitis outbreak in The Netherlands. J Infect Dis. 2001;184:1451–1455. doi: 10.1086/324327. [DOI] [PubMed] [Google Scholar]
  • 36.Schaap G.J., Bijkerk H., Coutinho R.A., Kapsenberg J.G., van Wezel A.L. The spread of wild poliovirus in the well-vaccinated Netherlands in connection with the 1978 epidemic. Prog Med Virol. 1984;29:124–140. [PubMed] [Google Scholar]

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