Table 2.
T1D (n = 50) | Control (n = 20) | P value | Adjusted P value† | |
---|---|---|---|---|
RO2:GFR by whole kidney, cortex, and medulla | ||||
Whole-kidney RO2:GFR (ms/mL/min) | 0.24 ± 0.04 | 0.32 ± 0.04 | <0.0001 | 0.0004 |
Cortex RO2:GFR (ms/mL/min) | 0.27 ± 0.05 | 0.36 ± 0.05 | <0.0001 | 0.003 |
Medullary RO2:GFR (ms/mL/min) | 0.21 ± 0.04 | 0.27 ± 0.05 | <0.0001 | 0.008 |
FSOC by whole kidney, cortex, and medulla | ||||
Whole-kidney FSOC (∆R2*) | 3.06 ± 1.26 | 2.77 ± 0.95 | 0.36 | 0.03 |
Cortex FSOC (∆R2*) | 1.35 ± 1.15 | 1.53 ± 1.48 | 0.61 | 0.57 |
Medullary FSOC (∆R2*) | 6.37 ± 2.60 | 5.73 ± 1.87 | 0.34 | 0.48 |
Data are presented as mean ± SD.
†Data are adjusted for sex and HbA1c for RO2:GFR, and sex, HbA1c, GFR, for FOSC.