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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Leukemia. 2020 Feb 12;34(7):1787–1798. doi: 10.1038/s41375-020-0732-1

Fig 1.

Fig 1

SRSF1 is upregulated in CD34+ CML progenitors. a. Heatmap indicating the expression of RNA-binding proteins that were differentially expressed in CD34+ cells from four normal bone marrow (nBM) and three CP CML (CP) samples as determined from RNA-sequencing. Bar scale refers to the Z-scores. b. SRSF1 transcript levels in nBM and CP CML samples were measured by qPCR (nBM=6, CP CML=10). Whiskers represent minimum and maximum values, lines within the boxes represent median values, p-values are determined by Student’s t-test. c. Western blot of SRSF1 levels in whole cell lysates obtained from CD34+ normal cord blood (nCB), normal bone marrow (nBM) or CP CML samples. CP#2 has been used across all three blots to show relative protein levels.