Abstract
Objetivo
Analizar las pautas de profilaxis antitrombótica en pacientes con fibrilación auricular (FA) mayores de 65 años y su adecuación a la evidencia.
Diseño
Estudio transversal.
Emplazamiento
Área de salud de Ourense, con 95.840 habitantes mayores de 65 años.
Participantes
Personas mayores de 65 años con FA no reumática, crónica o paroxística (411 casos; un 69,6% mayor de 75 años).
Mediciones principales
a) Variables sociodemográficas, antecedentes personales y riesgo de accidente cerebrovascular (ACV), y b) características diagnósticas de la FA, tratamiento antitrombótico prescrito y adecuación a la evidencia científica.
Resultados
En el momento del diagnóstico se prescribió anticoagulación oral (ACO) al 33% de los casos con riesgo alto. La probabilidad de recibir ACO se modificó por la edad (mayores de 75 años frente al grupo de 65-75 años; odds ratio, 0,32; intervalo de confianza del 95%, 0,18-0,59) y por la presencia de ACV previo (odds ratio, 2,02; intervalo de confianza del 95%, 1,16-3,55).
Conclusiones
Resulta insuficiente la prescripción de ACO profiláctica, sobre todo en los mayores de 75 años con riesgo alto de ACV y baja frecuencia de contraindicaciones; el porcentaje de inadecuación es del 73,4% en este grupo.
Palabras clave: Fibrilación aurículas, Envejecimiento, Prevención ictus, Tratamiento antitrombótico
Abstract
Aim
To describe the clinical practice in antithrombotic therapy to prevent stroke in older patients with atrial fibrillation (AF).
Design
Cross-sectional study.
Setting
Ourense's area with 95 840 inhabitants over 65 years.
Participants
Patients over 65 with non rheumatic AF, chronic or paroxistic; 411 cases, 69.6% older than 75 year.
Main measurements
Demographic characteristics, personal history, stroke risk, diagnostic characteristics of AF, antithrombotic treatment, and its adequacy.
Results
Only 33% high risk patients received oral anticoagulation (OCA) with warfarin at diagnosis. Some features were found to be significant independent risk factors for OCA: age (older than 75 vs 65-74 years; odds ratio =0.32; 95% confidence interval, 0.18-0.59), and prior stroke (odds ratio =2.02; 95% confidence interval, 1,16-3,55).
Conclusions
Warfarin prophylactic is insufficiently prescribed, especially in older than 75 years (with high baseline risk of stroke and no counter-indications). There was inadequate prescription in 73.4% cases.
Key words: Atrial fibrillation, Elderly, Stroke prevention, Antithrombotic therapy
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