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Journal of Neuroinflammation logoLink to Journal of Neuroinflammation
. 2020 Nov 23;17:352. doi: 10.1186/s12974-020-02034-6

Retraction Note: Bone mesenchymal stem cell-derivedexosomal microRNA-29b-3p preventshypoxic-ischemic injury in rat brain byactivating the PTEN-mediated Aktsignaling pathway

Kun Hou 1, Guichen Li 2, Jinchuan Zhao 1, Baofeng Xu 1, Yang Zhang 1, Jinlu Yu 1,, Kan Xu 1,
PMCID: PMC7685574  PMID: 33228701

Retraction to: J Neuroinflammation 17, 46 (2020)

https://doi.org/10.1186/s12974-020-1725-8

The authors have retracted this article [1] because they have been unable to replicate the results of their study. After publication they expanded the sample size and repeated the measurements, and found that miR-29b-3p was not always down-regulated in the rat MCAO model and OGD cell model. In addition, when the processing time was doubled, miR-29b-3p showed an upward trend. The conclusions presented are therefore not reliable. All authors agree with this retraction.

Contributor Information

Jinlu Yu, Email: jlyu@jlu.edu.cn.

Kan Xu, Email: xu_xukan@126.com.

Reference

  • 1.Hou K, Li G, Zhao J, Xu B, Yang Z, Yu J, Kan X. Bone mesenchymal stem cell-derived exosomal microRNA-29b-3p prevents hypoxic-ischemic injury in rat brain by activating the PTEN-mediated Akt signaling pathway. J Neuroinflammation. 2020;17:46. doi: 10.1186/s12974-020-1725-8. [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]

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