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. 2020 Nov 26;20:895. doi: 10.1186/s12879-020-05628-w

Correction to: The use of intravenous immunoglobulin gamma for the treatment of severe coronavirus disease 2019: a randomized placebo-controlled double-blind clinical trial

Naser Gharebaghi 1, Rahim Nejadrahim 1, Seyed Jalil Mousavi 1, Seyyed-Reza Sadat-Ebrahimi 2,, Reza Hajizadeh 3,
PMCID: PMC7689645  PMID: 33243191

Correction to: BMC Infect Dis (2020) 20:786

https://doi.org/10.1186/s12879-020-05507-4

Following publication of the original article [1], the author identified two errors in the Results section of the Abstract and in Table 2.

Table 2.

The relationship between study variables and mortality of patients with severe COVID-19

Mortality Unadjusted OR
(95% CI)
P-value
No Yes
Treatment Group 24 (61.5) 6 (30) 0.27 (0.08, 0.85) 0.025#
Control Group 15 (38.5) 14 (70) Ref
Age (years) 54 (44, 60) 60 (53.5, 70) 1.05 (1.01, 1.1) 0.014
Gender n (%) Male 27 (70) 14 (70) 0.96 (0.3, 3.12) 0.951
Female 12 (30) 6 (30) Ref
HTN n (%) 8 (23.3) 5 (25) 1.29 (0.36, 4.63) 0.694
DM n (%) 11 (20) 5 (25) 0.85 (0.25, 2.9) 0.793
Chronic lung disease n (%) 1 (6.6) 1 (5) 2 (0.12, 33.76) 0.630
HR/min 95 (90, 100) 95 (89, 108) 1.02 (0.96, 1.08) 0.543
Systolic BP (mmHg) 120 (120, 130) 120 (110, 130) 0.97 (0.93, 1.01) 0.173
Diastolic BP (mmHg) 80 (70, 80) 70 (70, 80) 0.95 (0.88, 1.01) 0.120
RR /min 19 (18, 22) 20 (18, 22) 0.98 (0.93, 1.04) 0.545
BT C° 37.1 (36.7, 37.7) 37.1 (36.75, 37.65) 1.26 (0.63, 2.52) 0.518
O2 saturation (%) 89 (87, 89) 85 (80, 88) 0.84 (0.74, 0.97) 0.015
WBC (1000/mm3) 5.1 (4.6, 7.4) 7.2 (5.1, 11.2) 1.00 (1.00, 1.00) 0.743
Hb (g/dl) 13.9 (12.6, 15) 13.5 (12.05, 15.25) 0.95 (0.8, 1.13) 0.566
Plt (1000/mm3) 210 (135, 247) 172.5 (139.5, 193) 1.00 (1.00, 1.00) 0.090
LDH (U/L) 520 (400, 687) 761 (560.5, 1021) 1.00 (1.00, 1.00) 0.003
BUN (mg/dl) 29 (25, 39) 64 (50, 129.5) 1.06 (1.02, 1.09) 0.001
Creatinine (mg/dl) 1 (1, 1.2) 1.2 (1.1, 1.55) 3.63 (0.95, 13.87) 0.059
K (mEq/L) 4 (3.7, 4.4) 4.2 (4.1, 4.3) 0.95 (0.8, 1.14) 0.616
Na (mEq/L) 138 (137, 139) 138 (135, 143.5) 1.04 (0.95, 1.14) 0.344
ESR 28 (20, 41) 40 (26, 49.5) 1.01 (0.99, 1.03) 0.424
AST (U/L) 31 (21, 39) 29.5 (15.5, 52.5) 1.00 (0.97, 1.02) 0.735
ALT (U/L) 34.5 (25, 41) 38.5 (29.5, 48) 1.01 (0.99, 1.02) 0.306
BS (mg/dl) 119 (105, 174) 126 (109.5, 184) 1.00 (0.99, 1.01) 0.845
PaO2 (mmHg) 46 (40, 50) 39.5 (34, 49) 0.92 (0.85, 0.99) 0.035
PCO2 (mmHg) 40 (35, 46) 38 (36, 39.5) 0.99 (0.91, 1.08) 0.798
HCO3 (mEq/L) 24 (22, 25) 24.5 (19.5, 26.5) 1.00 (0.89, 1.13) 0.946
pH 7.3 (7.3, 7.4) 7.3 (7.2, 7.4) 0.04 (0, 8.87) 0.243

The sentence currently reads:

“ The in-hospital mortality rate was significantly lower in the IVIg group compared to the control group (6 [20.0%] vs. 14 [48.3%], respectively; P = 0.022). “.

The sentence should read:

“ The in-hospital mortality rate was significantly lower in the IVIg group compared to the control group (6 [20.0%] vs. 14 [48.3%], respectively; P = 0.025). “.

Furthermore, the correct Table 2 is given below.

The original article [1] has been corrected.

Contributor Information

Seyyed-Reza Sadat-Ebrahimi, Email: Sadatr@tbzmed.ac.ir.

Reza Hajizadeh, Email: hajizadh.reza@gmail.com.

Reference

  • 1.Gharebaghi N, et al. The use of intravenous immunoglobulin gamma for the treatment of severe coronavirus disease 2019: a randomized placebo-controlled double-blind clinical trial. BMC Infect Dis. 2020;20:786. doi: 10.1186/s12879-020-05507-4. [DOI] [PMC free article] [PubMed] [Google Scholar]

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