Table 2.
Evaluation of the MIC and MBC of SurM 10K = just vesicles (>10K); SurE 10K = fractionated planktonic supernatant (<10K), and SurP = Total planktonic supernatant (pMVs included) versus E. coli ATCC25922, S. aureus ATCC 29233; S. mutans UA159; P. aeruginosa ATCC 27853; and F. nucleatum ATCC 25586.
| Bacterial Strains | SurM 10K MIC (µL/100 µL) |
SurM 10K MBC (µL/100 µL) |
SurE 10K MIC (µL/100 µL) |
SurE 10K MBC (µL/100 µL) |
SurP MIC (µL/100 µL) |
SurP
MBC (µL/100 µL) |
|---|---|---|---|---|---|---|
| E. coli ATCC 25922 | ≥50 | ≥50 | 10 | 50 | 10 | 50 |
| S. aureus ATCC 29213 | ≥50/ | ≥50 | 25 | 50 | 25 | ≥50 |
| S. mutans UA 159 | ≥50 | 50 | 44 | >50 | 44 | >50 |
| P. aeruginosa ATCC 27853 | 44 | >44 | 5.5 | 22 | 11 | 22 |
| F. nucleatum ATCC 25586 | ≥50 | ≥50 | 5 | 10 | 5 | 10 |