Table 5.

Characterization of blank and AZM-L-F2 formulations at Octanoic acid oil concentrations of low, medium, and high analyzed in the three diluents. Mean ± SD, n = 3.

Blank L-SEDDs					AZM-L-SEDDs
DW
Code	DS (nm)	Đ	ZP (mV)	T%	DS (nm)	Đ	ZP (mV)	T%
L-F2(L)	124.93 ± 1.5	0.64 ± 0.003	−17 ± 0.76	89.44 ± 0.26	143.1 ± 1.4	0.84 ± 0.02	−16.3 ± 0.87	90.47 ± 0.24
L-F2(M)	139.73 ± 1.31	0.59 ± 0.005	−17.1 ± 0.53	88.69 ± 0.08	148.43 ± 1.3	0.71 ± 0.003	−17.77 ± 0.96	89.03 ± 0.15
L-F2(H)	143.9 ± 1.64	0.68 ± 0.002	−18.23 ± 0.59	88.83 ± 0.32	267.8 ± 1.9	1 ± 0	−18.43 ± 0.97	77.96 ± 0.48
0.1 mM HCl (pH = 4)
L-F2(L)	104.65 ± 0.5	0.45 ± 0.002	0.27 ± 1.8	94.75 ± 0.1	113.7 ± 1.8	0.61 ± 0.07	0.086 ± 1.1	97.17 ± 0.55
L-F2(M)	113.53 ± 1.8	0.47 ± 0.003	−2.6 ± 0.4	93.77 ± 0.04	127.6 ± 1.5	0.54 ± 0.009	−0.58 ± 0.83	96.56 ± 0.57
L-F2(H)	130.37 ± 0.6	0.55 ± 0.002	0.24 ± 0.5	90.75 ± 0.07	136.7 ± 1.9	0.54 ± 0.02	0.62 ± 0.8	91.76 ± 0.58
SIF (pH = 6.8)
L-F2(L)	126.77 ± 1.2	1 ± 0	−3.61 ± 0.5	93.03 ± 0.11	149.77 ± 1.5	0.68 ± 0.01	−1.53 ± 0.17	89.1 ± 0.68
L-F2(M)	115.6 ± 1.1	1 ± 0	−4.18 ± 0.7	93.47 ± 0.12	159.47 ± 0.93	1 ± 0	−4.16 ± 1.02	86.62 ± 0.29
L-F2(H)	127.2 ± 1.4	1 ± 0	−4.44 ± 0.7	93.35 ± 0.13	226.3 ± 2.01	0.99 ± 0.006	−3.88 ± 0.69	75.02 ± 0.08

(Blank L-SEDDs, Blank liquid self-emulsifying drug delivery systems; AZM-L-SEDDs, Azithromycin-loaded self-emulsifying drug delivery systems DW, Distilled water; DS, Droplet size; Đ, Dispersity; ZP, Zeta potential; T%, Transmittance percentage; HCl, Hydrochloric acid).