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. 2020 Nov 4;11(11):758. doi: 10.3390/insects11110758

Table 1.

Active ingredients currently used in commercial fire ant baits in the USA.

Active Ingredient Source Mode of Action
Abamectin Natural compounds from bacterium Streptomyces avermitilis Selective high-affinity binder to glutamate-gated chloride channels
Fipronil Synthetic phenylpyrazole Blocker of gamma-aminobutyric acid (GABA)-gated chloride channels and glutamate-gated chloride channels
Hydramethylnon Synthetic trifluoromethyl aminohydrazone Metabolic inhibitor.
Indoxacarb Synthetic oxadiazine Blocker of neuronal sodium channels
Metaflumizone Synthetic semicarbazone Blocker of neuronal sodium channels
Methoprene Synthetic juvenile hormone analog Insect growth regulator
Pyriproxyfen Synthetic juvenile hormone analog Insect growth regulator
Spinosad Natural compounds from bacterium Saccharopolyspora spinosa Disruptor of acetylcholine neurotransmission