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. 2020 Nov 5;10(11):1513. doi: 10.3390/biom10111513

Figure 2.

Figure 2

Effect of eugenol on action potentials in small-sized TG neurons. (A) Eugenol (2 mM) inhibited action potentials (APs) following current injection (5 ms, 180 pA) in TG neurons. Traces of single APs were observed before (control) and after treatment with eugenol. (B) All data were normalized to controls (black bar) (n = 7). (C) Resting membrane potential (RMP) values: control, −53 mV; after treatment with eugenol, −24 mV; and after wash-out, −41 mV. (D) Eugenol suppressed the AP frequency in TG neurons. (E) All data were normalized to controls (black bar) (n = 6). * p < 0.05 versus control, ** p < 0.01 versus control. APs: action potentials, RMPs: Resting membrane potentials.