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. 2020 Nov 6;12(11):1264. doi: 10.3390/v12111264

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Aedes albopictus anphevirus (AealbAV) genome organization and conserved motif. (a) Genomic organization of AealbAV. Predicted ORFs are indicated with boxes. Positions of the 31-nt conserved motif are indicated by triangles. NP, nucleoprotein; TMD, Transmembrane domain; G, glycoproteins; ZnF, zinc-like finger; RdRP, RNA-dependent RNA polymerase. (b) Example of a mapping profile from 1 library (SRR458463) displaying the characteristic 3′–5′ transcription gradient typical of replicating monenegaviruses. (c) Sequences and logo of the 31-nt conserved motif as estimated by MEME.