Table 1.
Patients characteristics and blood measurements at time of admission and their univariate association with COVID-19 evolution.
| Patients Characteristics and Blood Measurements | All (n = 30) |
Non-Critical (n = 17) |
Critical (n = 13) |
p-Value |
|---|---|---|---|---|
| Age | 60.6 (6.1, 63.3) | 60.1 (51.7, 74.9) | 61.1 (55.2, 64.5) | 0.9833 |
| Gender (Male) | 20 (66.7%) | 12 (70.6%) | 8 (61.5%) | 0.6030 |
| Days of symptoms onset | 7.000 (6.000, 10.000) | 7.000 (4.000, 11.000) | 6.000 (5.000, 10.000) | 0.6439 |
| Days to hospital discharge | 8.000 (5.000, 14.000) | 5.000 (4.000, 6.000) | 15.500 (12.000, 22.000) | <0.001 |
| HT | 6 (20.0%) | 3 (17.6%) | 3 (23.1%) | 0.7134 |
| DM | 1 (3.3%) | 1 (5.9%) | 0 (0.0%) | 0.2810 |
| DLP | 5 (16.7%) | 2 (11.8%) | 3 (23.1%) | 0.4119 |
| OBESITY | 1 (3.3%) | 0 (0.0%) | 1 (7.7%) | 0.1900 |
| Leucocyte count (cells × 109/L) |
6310 (5310, 8860) | 6550 (5310, 9440) | 5970 (5120, 11370) | 0.4512 |
| Neutrophyl count (cells × 109/L) |
4440 (3920, 6650) | 4570 (3950, 7030) | 4200 (2900, 9370) | 0.4388 |
| Lymphocyte count (cells × 109/L) |
1215 (1040, 1310) | 1260 (1040, 1440) | 1180 (920, 1840) | 0.5030 |
| Ratio N/L | 4.26 (3.05, 5.08) | 4.19 (2.90, 5.08) | 4.33 (1.58, 7.95) | 0.8835 |
| Ferritin (ng/mL) | 711.7 (382.6, 1136.2) | 639.7 (270.6, 1136.2) | 783.7 (354.5, 2390) | 0.2330 |
| CRP (mg/dL) | 8.80 (5.07, 11.25) | 8.54 (4.74, 11.25) | 9.50 (5.00, 15.64) | 0.3909 |
| D-Dimer (mg/mL) | 691 (443, 860) | 703 (443, 860) | 679 (269, 1722) | 0.7695 |
| LDH (U/L) | 282 (244, 365) | 267 (238, 387) | 356 (243, 446) | 0.1713 |
| T lymphocyte count | 714 (497, 823) | 725 (497, 1119) | 647 (375, 1113) | 0.4025 |
| CD3+CD4+ count | 467 (303, 574) | 545 (445, 767) | 278 (178, 663) | 0.0180 |
| CD3+CD8+ count | 245 (171, 319) | 253 (145, 319) | 237 (87, 586) | 0.7064 |
| CD3+CD4+CD8+ count | 13 (8, 21) | 16 (9, 24) | 11 (4, 35) | 0.295 |
| CD3+CD4−CD8− count | 18.000 (12.000, 23.000) | 19 (12, 27) | 12 (5, 23) | 0.2249 |
| B Lymphocyte count | 112 (78, 162) | 121 (86, 185) | 79 (46, 197) | 0.3254 |
| Natural Killer count | 196 (154, 253) | 192 (140, 278) | 234 (128, 327) | 0.8017 |
| Ratio CD4+/CD8+ | 1.91 (1.58, 3.12) | 3.12 (1.58, 3.99) | 1.72 (0.78, 2.52) | 0.0135 |
| CD4+ MFI | 24861 (22770, 26259) | 26259 (24683, 27939) | 21820 (20666, 25157) | 0.0013 |
| CD8+ MFI | 25856 (23819, 27476) |
25948 (23819, 27607) | 25337 (22878, 32176) | 0.7855 |
HT: Arterial Hypertension; DM: diabetes; DLP: dyslipidemia; Ratio N/L: ratio Neutrophil to Lymphocyte; CRP: C-reactive protein; LDH: lactate dehydrogenase; MFI: median fluorescence intensity. Group medians and percentiles 25 and 75 (continuous variables) or absolute and relative frequencies (categorical variables) are showed. p-values are derived from a Mann–Whitney test (continuous variables) or an exact Fisher’s test (binary variables).