Table 1.

Databases used for target discovery.

Databases	Specific Information	Ref.
BRENDA http://www.brenda-enzymes.org	Enzyme and enzyme-ligand information source.	[33]
KEGG http://www.genome.jp/kegg	Database containing genomic information for functional interpretation and practical application.	[33]
PubChem https://pubchem.ncbi.nlm.nih.gov	Database for encompassing information on chemicals and biological activities.	[33]
TTD http://bidd.nus.edu.sg/group/ttd/ttd.asp	Therapeutic Target Database containing encompassing information about the drug resistance mutations, gene expressions, and target combinations data.	[33]
DrugBank http://www.drugbank.ca	Detailed drug data and drug-target information database.	[33]
SuperTarget http://bioinfapache.charite.de/supertarget	Drug-related information databases with more than >300,000 compound-target protein relations.	[33]
TDR targets http://tdrtargets.org	Database containing chemogenomic information for neglected tropical diseases.	[33]
STITCH http://stitch-beta.embl.de	Chemical-Protein interaction networks.	[28]
SMD http://genome-www5.stanford.edu	Database of raw microarray datasets.	[34]
Gene Expression Omnibus http://www.ncbi.nlm.nih.gov/geo	Database of raw microarray datasets.	[34]
caArray http://array.nci.nih.gov/caarray	Database of cancer-related microarray datasets.	[34]
CGAP database http://cgap.nci.nih.gov	Database of cancer-related microarray datasets.	[34]
Oncomine http://www.oncomine.org	Database of cancer-related microarray datasets.	[34]
UniHI http://www.unihi.org	Database of human molecular interaction networks.	[34]
Pathguide http://www.pathguide.org	Database of 702 biological pathway related resources and molecular interactions.	[34]
UniProt http://www.uniprot.org	Encompassing protein information center.	[34]
InterPro http://www.ebi.ac.uk/interpro	Database of protein domain information.	[34]