Table 2.
Effects of the feeding of peanut wholegrain, its germ-rich fraction, and ferulic acid on the amounts of protein expression in the hippocampus of SAMP8.
| Accession | Description | (R1 + H)/R1 | P8/R1 | (P8 + H)/P8 | (P8 + G)/P8 | (P8 + F)/P8 | |
|---|---|---|---|---|---|---|---|
| Glial fibrillary acidic protein | |||||||
| GFAP_MOUSE | Glial fibrillary acidic protein OS = Mus musculus GN = Gfap PE = 1 SV = 4 | ||||||
| Fold change (ratio) | 1.2 | 1.52 | 1.15 | 1.16 | 0.93 | ||
| p Value | 0.94 | 1 | 0.98 | 0.99 | 0.16 | ||
| A0MTM0_MOUSE | Glial fibrillary acidic protein (Fragment) OS = Mus musculus GN = Gfap PE = 2 SV = 1 | ||||||
| Fold change (ratio) | 1.28 | 1.09 | 1.07 | ||||
| p Value | 0.98 | 0.72 | 0.69 | ||||
| SOD | |||||||
| Q3U8W4_MOUSE | Superoxide dismutase OS=Mus musculus GN = Sod2 PE = 2 SV = 1 | ||||||
| Fold change (ratio) | NU | NU | 1.16 | 1.12 | 1.04 | ||
| p Value | 0.65 | 0.65 | 0.56 | ||||
| Q4FJX9_MOUSE | Superoxide dismutase OS = Mus musculus GN = Sod2 PE = 2 SV = 1 | ||||||
| Fold change (ratio) | NU | NU | 1.25 | 1.12 | 1.12 | ||
| p Value | 0.74 | 0.62 | 0.64 | ||||
| SODM_MOUSE | Superoxide dismutase [Mn], mitochondrial OS = Mus musculus GN = Sod2 PE = 1 SV = 3 | ||||||
| Fold change (ratio) | NU | NU | 1.23 | 1 | 1.16 | ||
| p Value | 0.73 | 0.5 | 0.62 | ||||
| Glutathione S-transferase | |||||||
| D3YVP6_MOUSE | Glutathione S-transferase Mu 7 OS = Mus musculus GN = Gstm7 PE = 4 SV = 2 | ||||||
| Fold change (ratio) | 1.02 | 1.04 | 0.94 | 0.83 | 0.89 | ||
| p Value | 0.59 | 0.67 | 0.33 | 0.12 | 0.2 | ||
| D3YX76_MOUSE | Glutathione S-transferase Mu 2 OS = Mus musculus GN = Gstm2 PE = 3 SV = 1 | ||||||
| Fold change (ratio) | 1.03 | 1.02 | 1.04 | 0.83 | |||
| p Value | 0.57 | 0.63 | 0.6 | 0.08 | |||
| A2AE91_MOUSE | Glutathione S-transferase, mu 4 OS = Mus musculus GN = Gstm4 PE = 3 SV = 1 | ||||||
| Fold change (ratio) | 1.01 | 1.05 | 0.93 | 0.83 | 0.85 | ||
| p Value | 0.52 | 0.69 | 0.3 | 0.11 | 0.1 | ||
| Q8R5I6_MOUSE | Glutathione S-transferase mu 4 OS = Mus musculus GN = Gstm4 PE = 2 SV = 1 | ||||||
| Fold change (ratio) | 1.02 | 1.09 | 0.92 | 0.81 | 0.91 | ||
| p Value | 0.55 | 0.83 | 0.3 | 0.08 | 0.25 | ||
| Glial high affinity glutamate transporter | |||||||
| A2APL7_MOUSE | Solute carrier Family 1 (Glial high affinity glutamate transporter), member 2 OS = Mus musculus GN = Slc1a2 PE = 2 SV = 1 | ||||||
| Fold change (ratio) | 0.72 | 0.91 | 1.04 | 0.86 | 0.78 | ||
| p Value | 0.02 | 0.22 | 0.61 | 0.14 | 0.16 | ||
| A2APL8_MOUSE | Solute carrier family 1 (Glial high affinity glutamate transporter), member 2 OS = Mus musculus GN = Slc1a2 PE = 4 SV = 1 | ||||||
| Fold change (ratio) | 0.73 | 1.05 | 0.93 | 0.73 | 1.25 | ||
| p Value | 0.01 | 0.61 | 0.29 | 0.02 | 0.92 | ||
| Q543U3_MOUSE | Solute carrier family 1 (Glial high affinity glutamate transporter), member 3 OS = Mus musculus GN = Slc1a3 PE = 2 SV = 1 | ||||||
| Fold change (ratio) | 0.93 | 1.19 | 0.82 | 0.84 | 1.07 | ||
| p Value | 0.38 | 0.87 | 0.13 | 0.17 | 0.63 | ||
| A2APM7_MOUSE | Solute carrier family 1 (Glial high affinity glutamate transporter), member 2 OS = Mus musculus GN = Slc1a2 PE = 4 SV = 1 | ||||||
| Fold change (ratio) | 0.79 | 0.94 | 0.63 | 0.41 | 1.45 | ||
| p Value | 0.11 | 0.31 | 0.15 | 0 | 0.96 | ||
| Q3UYK6_MOUSE | Solute carrier family 1 (Glial high affinity glutamate transporter), member 2 OS = Mus musculus GN = Slc1a2 PE = 2 SV = 1 | ||||||
| Fold change (ratio) | 0.79 | 0.81 | 0.94 | 0.76 | 1.25 | ||
| p Value | 0.08 | 0.19 | 0.35 | 0.06 | 0.94 | ||
| Calcium/calmodulin-dependent protein kinase | |||||||
| KCC2B_MOUSE | Calcium/calmodulin-dependent protein kinase type II sub-unit beta OS = Mus musculus GN = Camk2b PE = 1 SV = 2 | ||||||
| Fold change (ratio) | 0.99 | 1.3 | 0.64 | 0.94 | 1.17 | ||
| p Value | 0.39 | 0.99 | 0 | 0.27 | 0.99 | ||
| KCC2A_MOUSE | Calcium/calmodulin-dependent protein kinase type II sub-unit alpha OS = Mus musculus GN = Camk2a PE = 1 SV = 2 | ||||||
| Fold change (ratio) | 0.97 | 1.01 | 0.85 | 0.89 | 1.11 | ||
| p Value | 0.3 | 0.5 | 0.03 | 0.06 | 0.98 | ||
| E9Q1V9_MOUSE | Calcium/calmodulin-dependent protein kinase type II sub-unit delta OS = Mus musculus GN = Camk2d PE = 4 SV = 1 | ||||||
| Fold change (ratio) | 0.93 | 1.07 | 0.7 | 0.91 | 1.2 | ||
| p Value | 0.21 | 0.86 | 0 | 0.22 | 0.99 | ||
| Sodium- and chloride-dependent GABA transporter | |||||||
| S6A11_MOUSE | Sodium- and chloride-dependent GABA transporter 3 OS = Mus musculus GN = Slc6a11 PE = 1 SV = 2 | ||||||
| Fold change (ratio) | 1.14 | 0.92 | 1.13 | 1.31 | 1.67 | ||
| p Value | 0.78 | 0.29 | 0.86 | 0.9 | 0.99 | ||
| Glutamine synthase | |||||||
| GLNA_MOUSE | Glutamine synthetase OS = Mus musculus GN = Glul PE = 1 SV = 6 | ||||||
| Fold change (ratio) | 0.9 | 1 | 1.01 | 0.91 | 0.83 | ||
| p Value | 0.23 | 0.51 | 0.56 | 0.27 | 0.06 | ||
| Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein | |||||||
| A2A5N2_MOUSE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, | ||||||
| beta OS = Mus musculus GN = Ywhab PE = 2 SV = 1 | |||||||
| Fold change (ratio) | 0.95 | 1.03 | 0.82 | 0.81 | 0.88 | ||
| p Value | 0.24 | 0.75 | 0 | 0.01 | 0.05 | ||
| Q5SS40_MOUSE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, | ||||||
| epsilon polypeptide OS = Mus musculus GN = Ywhae PE = 2 SV = 1 | |||||||
| Fold change (ratio) | 1.01 | 1.04 | 0.9 | 0.9 | 0.89 | ||
| p Value | 0.53 | 0.83 | 0.04 | 0.03 | 0.01 | ||
| Dihydropteridine reductase | |||||||
| D3YWR7_MOUSE | Dihydropteridine reductase OS = Mus musculus GN = Qdpr PE = 4 SV = 1 | ||||||
| Fold change (ratio) | NU | NU | NU | 1.28 | NU | ||
| p Value | 0.79 | ||||||
| DHPR_MOUSE | Dihydropteridine reductase OS = Mus musculus GN = Qdpr PE = 1 SV = 2 | ||||||
| Fold change (ratio) | NU | NU | NU | 1.55 | NU | ||
| p Value | 0.88 | ||||||
| Tubulin alpha | |||||||
| TBA1A_MOUSE | Tubulin alpha-1A chain OS = Mus musculus GN = Tuba1a PE = 1 SV = 1 | ||||||
| Fold change (ratio) | 0.99 | 1.08 | 0.96 | 0.97 | 0.96 | ||
| p Value | 0.19 | 1 | 0 | 0.04 | 0.03 | ||
| TBA1C_MOUSE | Tubulin alpha-1C chain OS = Mus musculus GN = Tuba1c PE = 1 SV = 1 | ||||||
| Fold change (ratio) | 0.99 | 1.07 | 0.95 | 0.97 | 0.97 | ||
| p Value | 0.39 | 1 | 0.01 | 0.02 | 0.05 | ||
| O89052_MOUSE | Alpha-tubulin (Fragment) OS = Mus musculus GN = Tuba1b PE = 2 SV = 1 | ||||||
| Fold change (ratio) | 1 | 1.16 | 0.9 | 0.97 | 1.02 | ||
| p Value | 0.46 | 1 | 0 | 0.12 | 0.77 | ||
| Synapsin-2 | |||||||
| SYN2_MOUSE | Synapsin-2 OS = Mus musculus GN = Syn2 PE = 1 SV = 2 | ||||||
| Fold change (ratio) | 0.84 | 0.97 | 0.77 | 0.79 | 1.01 | ||
| p Value | 0.01 | 0.31 | 0 | 0 | 0.59 | ||
| Hemoglobin subunit alpha | |||||||
| HBA_MOUSE | Hemoglobin subunit alpha OS = Mus musculus GN = Hba PE = 1 SV = 2 | ||||||
| Fold change (ratio) | 0.97 | 0.8 | 1.2 | 1.19 | 1.06 | ||
| p Value | 0.31 | 0 | 1 | 1 | 0.88 | ||
| Sodium- and chloride-dependent GABA transporter | |||||||
| S6A11_MOUSE | Sodium- and chloride-dependent GABA transporter 3 OS = Mus musculus GN = Slc6a11 PE = 1 SV = 2 | ||||||
| Fold change (ratio) | 1.14 | 0.92 | 1.13 | 1.31 | 1.67 | ||
| p Value | 0.78 | 0.29 | 0.86 | 0.9 | 0.99 | ||
| Hemoglobin subunit beta | |||||||
| HBB1_MOUSE | Hemoglobin subunit beta-1 OS = Mus musculus GN = Hbb-b1 PE = 1 SV = 2 | ||||||
| Fold change (ratio) | 0.94 | 0.79 | 1.14 | 1.17 | 0.99 | ||
| p Value | 0.06 | 0 | 1 | 1 | 0.37 | ||
| E9Q223_MOUSE | Hemoglobin subunit beta-1 (Fragment) OS = Mus musculus GN = Hbb-b1 PE = 3 SV = 1 | ||||||
| Fold change (ratio) | 0.9 | 0.79 | 1.12 | 1.11 | 0.92 | ||
| p Value | 0.01 | 0 | 0.97 | 0.97 | 0.1 | ||
| HBB2_MOUSE | Hemoglobin subunit beta-2 OS = Mus musculus GN = Hbb-b2 PE = 1 SV = 2 | ||||||
| Fold change (ratio) | 0.98 | 0.84 | 1.12 | 1.16 | 0.99 | ||
| p Value | 0.32 | 0 | 0.98 | 1 | 0.44 | ||
R1: senescence-accelerated resistant mice (SAM-R1) group fed with basal diet; P8: senescence-accelerated mouse prone/8 (SAMP8) group fed with basal diet; R1 + H: SAM-R1 group fed with basal diet with added peanut wholegrain; P8 + H: SAMP8 group fed with basal diet with added peanut wholegrains; P8 + G: SAMP8 group fed with basal diet with added germ-rich fraction of wholegrain; P8 + F: SAMP8 group fed with basal diet with added ferulic acid. Accession or number is a sries of codes or numbers that are assigned to the identified protein by NCBI. Fold change is expressed as the ratio between two groups (NU group/DE group). p values higher than 0.95 show that the protein content is statistically higher in the numerator group than the denominator group. p values lower than 0.05 show that protein content is statistically higher in the denominator group than that of the numerator group. Columns filled with NU and DE show that proteins (enzymes) corresponding to the column were detected in only the NU and DE groups, respectively. PE, protein evidence; SV, structural variance; GABA, gannma-aminobutylic acid, SOD, superoxide dismutase.