Table 1.
Specifics on the animals used in this study.
| Animal | Age (Yrs) | Condition | Days p.i. | Terminal Plasma Viral Load (log10/mL) | Tissue Viral Load (log10/µg RNA) | |||
|---|---|---|---|---|---|---|---|---|
| Caudate | Frontal Cortex | Hippo-Campus | Spleen | |||||
| 17T | 5.1 | SIVE | 65 | 8.8 | 6.3 | 7.2 | 7.2 | 8.2 |
| 34T | 2.7 | SIVE | 92 | 7.8 | 7.8 | 8.1 | 7.7 | 7.8 |
| 21T | 5.4 | Meth-SIVE | 92 | 8.5 | 7.5 | 7.3 | 6.6 | 7.5 |
| 32T | 4.0 | Meth-SIVE | 78 | 7.7 | 7.3 | 7.7 | 7.6 | 8.0 |
Animals used for isolation of brain macrophages/microglia, including age at necropsy and condition (meth indicates pre-infection ramp-up and maintenance for 60 days followed by inoculation with SIV, and then maintained on meth until necropsy). Days p.i. is time from SIV inoculation to necropsy. Viral loads were determined as described in Methods.