Table 2. Minimum inhibitory concentration (MIC) of AMPs and rifampicin (RIF) against S. aureus isolates.
S. aureus isolates | Antimicrobial agent MIC (mg/L) | Resistance phenotype | |||
---|---|---|---|---|---|
HNP-1 | hBD-1 | hBD-3 | RIF | ||
SA-1 | 8 | 4 | 4 | 0.004 | AMP, CIP |
SA-2 | 4 | 8 | 0.5 | 0.004 | CIP |
SA-3 | 8 | 16 | 8 | 0.008 | CIP |
SA-4 | 4 | 2 | 0.5 | 0.004 | AMP, CIP, ERY, AZM |
SA-5 | 4 | 4 | 1 | 0.008 | CIP, DOX |
SA-6 | 0.5 | 1 | 1 | 0.004 | CIP, DOX |
SA-7 | 2 | 4 | 0.5 | 0.004 | AMP, ERY, AZM |
SA-8 | 4 | 8 | 1 | 0.008 | AMP, AZM |
SA-9* | 0.5 | 4 | 0.5 | 0.016 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-10* | 0.5 | 8 | 1 | 0.016 | FOX, GEN, AMN |
SA-11* | 4 | 2 | 4 | 0.016 | FOX, AMP, GEN, AMN |
SA-12* | 2 | 16 | 8 | 0.016 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-13* | 2 | 4 | 4 | 0.008 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-14* | 8 | 4 | 1 | 0.008 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-15* | 4 | 8 | 0.5 | 0.008 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-16* | 4 | 16 | 0.5 | 0.004 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-17* | 16 | 2 | 1 | 0.008 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-18* | 4 | 2 | 0.5 | 0.004 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-19* | 1 | 2 | 0.5 | 0.004 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-20* | 4 | 16 | 0.5 | 0.032 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-21* | 4 | 8 | 1 | 0.016 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-22* | 16 | 4 | 4 | 0.016 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-23* | 4 | 16 | 0.5 | 0.004 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-24* | 16 | 8 | 0.5 | 0.032 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-25* | 4 | 8 | 1 | 0.008 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-26* | 16 | 8 | 4 | 0.016 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
SA-27* | 4 | 16 | 2 | 0.032 | FOX, AMP, CIP, LVX, DOX, ERY, AZM, GEN, AMN |
Notes:
MRSA.
FOX, cefoxitin; AMP, ampicillin; CIP, ciprofloxacin; LVX, levofloxacin; DOX, doxycycline; ERY, erythromycin; AZM, azithromycin; GEN, gentamicin; AMN, amikacin; RIF, rifampicin.