Table 2.
Projected trial formulation compositions and the observed response of sildenafil citrate (SLC)-loaded nanoemulsion (NE) formulations, as recommended by the mixture design.
| Formulation Code | Independent Variables (Mixture Components) | Dependent Variables (Responses) | ||
|---|---|---|---|---|
| X1 (gm) | X2 (gm) | X3 (gm) | Y1 (nm) | |
| NE-1 | 0.1 | 0.3 | 0.6 | 528.17 |
| NE-2 | 0.3 | 0.3 | 0.4 | 233.6 |
| NE-3 | 0.1 | 0.6 | 0.3 | 65.07 |
| NE-4 | 0.3 | 0.6 | 0.1 | 382 |
| NE-5 | 0.15 | 0.375 | 0.475 | 855.5 |
| NE-6 | 0.25 | 0.375 | 0.375 | 199.5 |
| NE-7 | 0.15 | 0.525 | 0.325 | 165.84 |
| NE-8 | 0.25 | 0.525 | 0.225 | 470 |
| NE-9 | 0.2 | 0.3 | 0.5 | 720.49 |
| NE-10 | 0.1 | 0.45 | 0.45 | 135.09 |
| NE-11 | 0.3 | 0.45 | 0.25 | 296.22 |
| NE-12 | 0.2 | 0.6 | 0.2 | 602.21 |
| NE-13 | 0.2 | 0.45 | 0.35 | 532.56 |
| NE-14 | 0.1 | 0.3 | 0.6 | 300.5 |
| NE-15 | 0.3 | 0.3 | 0.4 | 512.4 |
| NE-16 | 0.1 | 0.6 | 0.3 | 103.5 |