Table 5.
Spatial distribution of cells and macrophages co-expressing MMP-2 and MMP-8
| Parameter (n = 7 PP meshes) | Distance from Fibers | |||||
|---|---|---|---|---|---|---|
| Zone1 000–050 µm | Zone2 050–100 µm | Zone3 100–150 µm | Zone4 150–200 µm | Zone5 200–250 µm | Zone6 250–350 µm | |
| % MMP-2+ cells | 42.8 (5.9) | 31.7 (5.9) | 30.8 (6.1) | 31.8 (5.7) | 32.5 (6.2) | 32.9 (5.8) |
| % CD68+MMP-2+ cells | 38.6 (4.7) | 21.2 (3.8) | 16.3 (3.4) | 13.6 (2.7) | 12.0 (2.7) | 10.5 (2.6) |
| % CD68+MMP-2+/CD68+ | 58.1 (7.9) | 51.6 (8.3) | 52.8 (8.7) | 55.2 (8.8) | 56.2 (9.1) | 56.9 (8.8) |
| % MMP-8+ cells | 2.5 (1.0) | 2.2 (0.6) | 2.2 (0.8) | 2.9 (1.4) | 2.8 (1.4) | 2.6 (1.1) |
| % CD68+MMP-8+ cells | 1.7 (0.8) | 0.8 (0.3) | 0.7 (0.3) | 0.8 (0.5) | 0.5 (0.2) | 0.6 (0.4) |
| % CD68+MMP-8+/CD68+ | 3.1 (1.4) | 2.5 (0.8) | 3.0 (1.0) | 3.7 (1.9) | 4.3 (1.7) | 5.4 (3.4) |
Percentages of cells (e.g., MMP2+ cells) and macrophages (e.g., CD68+MMP-2+ cells) co-expressing MMPs with respect to all cells, and the proportions of co-expressing macrophages with respect to the total number of macrophages (e.g., CD68+MMP-2+/CD68+) in each regional zone. The data are presented as mean (SE)