In the original article, there was a mistake in the legend for **Figure 6** as published. **The results were error in Figure 6A, so the legend of Figure 6 was revised**. The correct legend appears below.
Figure 6.
The expression of autophagy- and apoptosis-related protein expression in spinal neuron cells by western blot. *p < 0.05 compared with the control group; #p < 0.05 compared with the model group; ∧p < 0.05 compared with the LXA4 group. Experiments were repeated three times for each group. Data are presented as means ± SD. One-way analysis of variance (ANOVA) was used for comparisons among groups followed by Dunnett's t-test.
**Figure 6. The expression of autophagy- and apoptosis-related protein expression in spinal neuron cells by western blot. *p < 0.05 compared with the control group; #p < 0.05 compared with the model group; ∧p < 0.05 compared with the LXA4 group. Experiments were repeated three times for each group. Data are presented as means ± SD. One-way analysis of variance (ANOVA) was used for comparisons among groups followed by Dunnett's t-test. **
In the original article, there was a mistake in **Figure 6** as published. **The results of Figure 6A were error, so the results of Figure 6A were deleted in Figure 6 **. The corrected *Figure 6** appears below.
In the original article, there was an error. **The levels of TNF (orb79138-480), IL-1β (orb79117), IL-18 (orb107403), IL-4 (orb303658), IL-10 (orb76364), and TGF-β1 (orb7087) (all from Biorbyt, Cambridge, United Kingdom) in the spinal dorsal horn, dorsal root ganglion, and spinal neurons were measured following the instructions of the respective ELISA kits.**
A correction has been made to **Materials and Methods**, **ELISA**, **Page 3**:
**The levels of TNF-α (orb452907), IL-1β (orb453587), IL-18 (orb107403), IL-4 (orb303658), IL-10 (orb76364), and TGF-β1 (orb7087) (all from Biorbyt, Cambridge, United Kingdom) in the spinal dorsal horn and dorsal root ganglion were measured following the instructions of the respective ELISA kits. **
In the original article, there was an error. **The Effect of LXA4 on the Expression of the NLRP3 Inflammasome and Autophagy-Related Proteins in TNF-α-Induced Neuronal Cells in vitro**
A correction has been made to **Results**, **The Effect of LXA4 on the Expression of the NLRP3 Inflammasome and Autophagy-Related Proteins in TNF-α-Induced Neuronal Cells in vitro**, **Page 9**:
**The Effect of LXA4 on the Expression of Autophagy-Related Proteins in TNF-α-Induced Neuronal Cells in vitro**
In the original article, there was an error. **The levels of proinflammatory (TNF-α, IL-1β, and IL-18) and anti-inflammatory (IL-4, IL-10, TGF-β) mediators are shown in Figure 6A. Compared with control group, the levels of TNF-α, IL-1β, and IL-18 clearly increased in other groups (p < 0.05). Administration of LXA4 led to a marked reduction in the expression levels of TNF-α, IL-1β, and IL-18 compared with the model group, while the effect of LXA4 was weakened by LY294002 (p < 0.05). Compared with control group, the levels of TNF-α, IL-1β, and IL-18 clearly obviously decreased in other groups (p < 0.05). Meanwhile, the expression of IL-4, IL-10, and TGF-β was significantly increased in the LXA4 group compared with the model group (p < 0.05). Similar to the in vivo results, LAX4 treatment markedly upregulated the contents of anti-inflammatory factors and weakened the effect of LY294002. The expression of autophagy-related proteins were also measured in vitro (Figure 6B). Compared with the control group, the expression of MAP1LC3B/MAP1LC3A, Beclin-1, and PI3KC3 was significantly decreased in other groups (p < 0.05). The expression of caspase-1 was significantly increased after TNF-α stimulated, compared with control group (p < 0.05). LY294002 administration further decreased the expression levels of these proteins. Meanwhile, treatment with LXA4 significantly increased the expression of autophagy-related proteins and weakened the effect of LY294002 (p < 0.05).**
A correction has been made to **Results**, **The Effect of LXA4 on the Expression of Autophagy-Related Proteins in TNF-α-Induced Neuronal Cells in vitro**, **Page 10**:
**The expression of autophagy-related proteins were also measured in vitro (Figure 6). Compared with the control group, the expression of MAP1LC3B/MAP1LC3A, Beclin-1, and PI3KC3 was significantly decreased in other groups (p < 0.05). The expression of caspase-1 was significantly increased after TNF-α stimulated, compared with control group (p < 0.05). LY294002 administration further decreased the expression levels of these proteins. Meanwhile, treatment with LXA4 significantly increased the expression of autophagy-related proteins and weakened the effect of LY294002 (p < 0.05). **
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.