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Pharmacokinetic values obtained for FV activity following a single bolus dose of 15 mg kg−1 of FFP.
| Parameter | Value ± SE |
|---|---|
| AUC (IU dL−1) | 310 ± 22.6 |
| t½ (h) | 13.5 ± 1.18 |
| Cmax (IU dL−1) | 16 ± 0.78 |
| CL (mL kg−1 h−1) | 0.05 ± 0.003 |
| AUMC (IU dL−1) | 6039 ± 926 |
| MRT (h) | 19.5 ± 1.7 |
| Vss (mL kg−1) | 0.9 ± 0.05 |
AUC, area under the curve; Cmax, maximum plasma concentration; CL, clearance; AUMC, area under the first moment curve; MRT, mean residence time; Vss, volume of distribution at steady state.
