Table 2.
Predicted and observed FV activity over 48 h, after administration of a loading dose of 20 mL kg−1, followed by continuous infusion of 1.5 mL kg−1 h−1. Target goal FV activity to prevent bleeding complications was set at ≥20% (IU dL−1). Normal FV activity ranges from 50 to 150% (IU dL−1 ).
Time (h) | Predicted FV Activity (IU dL−1 or%) | Observed FV Activity (IU dL−1 or%) |
---|---|---|
0 | 22 | 17 |
3 | 23 | 32 |
12 | 27 | 28 (at hour 13) |
15 | 27 | 21 (at hour 16.5) |
18 | 28 | 20 |
20 | 28 | 53* |
36 | 30 | 108* (at hour 33) |
48 | 31 | 127* (at hour 42) |
Indicates transplanted orthotopic liver function.