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. Author manuscript; available in PMC: 2021 Mar 10.
Published in final edited form as: Nature. 2020 Sep 10;587(7835):673–677. doi: 10.1038/s41586-020-2749-z

Extended data Figure 4. Density maps and structural models of cGAS-nucleosome (reconstituted, 1:1) complex.

Extended data Figure 4.

a - f. The density maps (grey mesh) of histones H2A, H2B, H3, H4, part of mouse cGAS catalytic domain, and the Widom 601 nucleosome positioning sequence DNA contoured at 3σ. The protein and DNA structures fitted into the density map are shown by the stick models.