Skip to main content
Frontiers in Nutrition logoLink to Frontiers in Nutrition
. 2020 Nov 17;7:573536. doi: 10.3389/fnut.2020.573536

Corrigendum: PTEN: A Thrifty Gene That Causes Disease in Times of Plenty?

Ajit Venniyoor 1,*
PMCID: PMC7705169  PMID: 33282899

In the original article, there was a mistake in **Figure 1** as published.

Figure 1.

Figure 1

Deficiency of nutrients in utero, specifically proteins and choline lead to upregulation of DNMT3a and possibly 1, resulting in promoter methylation and suppression of PTEN, to varying degrees. This adapts the offspring to a nutritionally constrained post natal environment with efficient fat storage and reduced thermogenesis. If the birth environment continues to lack nutrition, the organism is well-adapted for survival, but in an obesogenic environment, would result in obesity, metabolic disorders, and cancer.

**The caption in Box 6 (from top, right branch) reads “INCREASED THERMOGENESIS”**.

The corrected **Figure 1** appears below.

The caption should read “DECREASED THERMOGENESIS”.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.


Articles from Frontiers in Nutrition are provided here courtesy of Frontiers Media SA

RESOURCES