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Acknowledgements
The authors gratefully appreciated the participation of patients in this study. We thank BingXu and Junhui Li for their excellent assistance for sample preparation and data processing. This work was supported by the Ministry of Science and Technology of the People’s Republic of China (2020YFC0844900, 2020YFC0841700, and 2020YFC0848700), the National Natural Science Foundation of China (81470566, 81670765, 81772165, and 81974303), the China Primary Health Care Foundation-Youan Medical Development Fund (BJYAYY-2020PY-01) and the funds from Neoline, Gbio and Quanterix. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Supporting Information
Footnotes
Compliance and ethics
The author(s) declare that they have no conflict of interest. This study and all the relevant experiments were approved by the Beijing Youan Hospital Research Ethics Committee, and written informed consent was obtained from each participant in accordance with the Declaration of Helsinki.
Contributed equally to this work
Contributor Information
Liangzhi Xie, Email: liangzhi@yahoo.com.
Ronghua Jin, Email: jin_eagle@sina.com.
Yingmei Feng, Email: yingmeif13@sina.com.
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