Table 2.
Vascular parameters in participants with CKD and controls
| Variable | CKD (n=64) | Control (n=17) | P Value |
| FMDBA (%) | 3.5±2.8 | 5.5±3.2 | 0.02 |
| FMDBA (mm) | 0.14±0.10 | 0.20±0.11 | 0.04 |
| Baseline FMD diameter (mm) | 4.1±0.7 | 3.7±0.6 | 0.02 |
| Resting shear rate (s−1) | 132±47 | 121±38 | 0.39 |
| Hyperemic shear rate (s−1) | 644±225 | 831±271 | 0.01 |
| Time to peak FMDBA (s) | 57±22 | 44±16 | 0.03 |
| Brachial artery dilation to nitroglycerin (%) | 18.2±9.7 | 26.0±7.3 | 0.01 |
| Baseline nitroglycerin diameter (mm) | 4.1±0.7 | 3.8±0.6 | 0.13 |
| Carotid-femoral PWV (cm/s) | 1071±336 | 732±128 | <0.001 |
| Carotid-radial PWV (cm/s) | 1003±246 | 955±165 | 0.46 |
| Carotid artery compliance (mm/mm Hg×10−1) | 0.76±0.32 | 0.78±0.18 | 0.65 |
| Carotid β-stiffness index (A.U.) | 11.8±4.6 | 8.7±2.0 | <0.001 |
| Carotid IMT (mm) | 0.67±0.19 | 0.58±0.09 | 0.04 |
| Carotid systolic BP (mm Hg) | 134±19 | 116±17 | 0.001 |
| Brachial mean arterial BP (mm Hg) | 90±14 | 87±10 | 0.41 |
Data are mean±SD. n=14 controls and n=49 participants with CKD were administered nitroglycerin. n=56 participants with CKD and all (n=17) control participants had measurements of carotid artery compliance and β-stiffness index. n=64 participants with CKD and all (n=17) control participants had measurements of carotid IMT. N=62/N=63 participants with CKD and n=16/n=17 control participants had successful measurements of carotid-femoral PWV and carotid-radial PWV, respectively. All vascular parameters were assessed in the supine position. FMDBA, brachial artery flow-mediated dilation; PWV, pulse-wave velocity; IMT, intimal medial thickness.