Phenotypes of Ppara knockout (KO) mice
(a) Prepulse inhibition (PPI) test. The values represent the mean ± standard error. The average of startle response was analyzed by using unpaired t-test. The PPI data were analyzed using a two-way repeated-measures ANOVA (genotype effect, p = 0.0475), followed by Fisher's LSD test.
(b) The marble-burying test. The values represent the mean ± standard error. The data were analyzed using unpaired t-tests.
(c) Typical images of dendritic spines in Ppara KO mice. Scale bar = 1 µm.
(d) Average spine density in wild-type (WT) (4 mice, ten cells) and Ppara KO (4 mice, 10 cells) mice. The values represent the mean ± standard error. The data were analyzed using the unpaired t-test.
(e) Morphological classification of spines in WT (4 mice, ten cells) and Ppara KO (4 mice, ten cells) mice. Spines were classified as immature (filopodia + thin) spines and mature (stubby + mushroom + branched) spines. The values represent the mean ± standard error. The data were analyzed using the unpaired t-test.