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. 2020 Dec 4;25(23):5728. doi: 10.3390/molecules25235728

Figure 2.

Figure 2

(A) Effect of treatment with 10 µM inhibitor 4 (72 h) on cell viability of MDA-MB-468 (MDA), Colo205 (Colo) and HCT116 (HCT) cells compared to vehicle-treated control (Ctrl) cells. (B) Effect of treatment with 10 µM inhibitor 4 (48 h) on apoptosis of MDA-MB-468 (MDA) and Colo205 (Colo) cells compared to vehicle-treated control (Ctrl) cells. (C) Effect of treatment with 10 µM inhibitor 4 (24 h) on STAT3 phosphorylation status in MDA-MB-468 (MDA) and Colo205 (Colo) cells compared to vehicle treatment. (D) Effect of treatment with 10 µM inhibitor 4 (24 h) on E2F1 protein expression in MDA-MB-468 cells compared to vehicle-treated control (Ctrl). *** p < 0.001 (very significant).