Table 6.
Effect of storage on the properties of the optimized proniosomal formula and the corresponding niosomal formula.
| Parameter | Proniosomal Formula | Niosomal Formula | ||
|---|---|---|---|---|
| Fresh | Stored | Fresh | Stored | |
| Drug Content (%) | 97.44 ± 1.69 | 96.95 ± 1.32 | 95.94 ± 1.27 | 90.22 ± 1.44 |
| EE (%) | 89.94 ± 2.31 | 87.86 ± 1.82 | 90.78 ± 1.52 | 83.02 ± 2.11 |
| Q12h (%) | 70.89 ± 1.62 | 68.94 ± 0.90 | 61.42 ± 1.71 | 53.12 ± 0.97 |
Notes: Each value is presented as mean ± SD (n = 3), the optimized Curcumin-loaded proniosomes is F5. Abbreviations: EE, entrapment efficiency; Q12h, % drug released after 12 h.