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Caco-2 monolayer transport system (a) at seeding time (t = 0 days) and (b) 21 days (t = 21 days) after seeding. Phenolic compounds will be applied in the apical compartment followed by quantification of the content in both compartments as well as the intracellular concentration; AC: medium sample of apical compartment, IC: washed and harvested cells for quantifying intracellular content, BC: medium sample of basolateral compartment.
