Figure 8. Single-cell RNA-Seq analysis reveals an enrichment of activity-associated gene expression in male OSNs expressing Olfr910, Olfr912, and Olfr1295.

(A) Chemosensory receptor-independent UMAP embedding of 17,666 singly sequenced mature OSNs. OSNs expressing Olfr910, Olfr912, Olfr1295, Olfr1437, and Olfr235 are highlighted. (B) Gene expression analysis identified activity-associated genes S100a5, Ptprn, Pcp4l1, and Nrp1 to be enriched amongst OSNs expressing Olfr910, Olfr912, and Olfr1295. (C) UMAP representations of S100a5, Ptprn, Pcp4l1, and Nrp1 show a tendency toward higher expression where OSNs expressing Olfr910, Olfr912, and Olfr1295 are localized.