Abstract
Introduction: Laser acupuncture is one of the low-level laser therapy (LLLT) methods, replacing the traditional technique of Chinese needle acupuncture. This article describes the main principles and parameters of laser acupuncture based on the analysis of 35 years of successful experience in applying the method in Russia.
Methods: The search of the literature on laser acupuncture was made in the Russian Medical Library and the Russian State Library (1498 publications in Russian), and PubMed/Medline (117 publications in English). 96 studies on laser acupuncture techniques were selected and a narrative review was conducted.
Results: The optimal parameters of the technique were worked out by Russian specialists in the 1970s, and are perfectly confirmed by the wide practice of clinical application. The literature review showed that the most optimal parameters of laser acupuncture are wavelength - 635 nm (red spectrum), power - no more than 2-3 mW, the diameter of special nozzle attachment - not more than 1-1.5 mm, and exposure - 20-40 s (for corporal points) or 5-10 s (for auricular points). The impact on acupuncture points (APs) is carried out consistently in accordance with the recipe (protocol), with no more than 10-12 daily procedures.
Conclusion: Laser acupuncture is a very effective and reproducible technique to treat patients with different diseases. Any specialist can apply this method because of its simplicity, but using the most effective parameters.
Keywords: Low-level laser therapy, Laser acupuncture, Low-intensity laser light, Laser parameters
Introduction
Low-level laser therapy (LLLT) is a rapidly developing area of modern clinical medicine. Every year, the number of studies on the biomodulating effects of low-intensity laser illumination and the possibilities of laser therapy in various fields of medicine is growing. However, in publications published in English, unsuitable illumination parameters are often used, and these parameters, in our experience, are not suitable for influencing a living organism. Russian LLLT researchers still publish mostly in Russian, so that the treasure of their decades of experience is still mostly unknown to the international scientific community today. The purpose of this article is to present and examine the findings of Russian research in the field of laser acupuncture in particular.
Laser acupuncture is one of the two LLLT techniques for general (systemic) exposure in humans and animals. Percutaneous or intravenous laser blood illumination is the second technique. It is recommended to combine these methods with local laser illumination (in the projection of a nidus) to achieve the most effective LLLT.1
In the English-speaking environment, it is commonly assumed that F. M. W. Plog2 pioneered the use of laser light for acupuncture in 1973–74.3 Since 1979, Zhou has widely used this technique to treat surgical patients in China.4 In Russia (to be more precise, in the USSR), laser acupuncture began to be used alongside other LLLT methods in the period from 1970 to 1972 for treating patients with asthma, alopecia, hypertension, and some neurological diseases.5-7
The first Russian publications devoted to the study of the peculiarities of acupuncture point (AP) exposure to the laser light, the fundamentals and mechanisms of the biοmodulating effect of LLLT, and the substantiation of optimal parameters of the technique appeared much earlier.8,9 The Russian founders of modern laser acupuncture methodology were Anischenko et al10 and Buylin.11 The wonderful Ukrainian school should not be left unmentioned.12,13
In the current study, we present the results of successful experience in the application of laser acupuncture in Russia, where hundreds of thousands of grateful patients of different ages (from 1 week to 100 years) have been effectively treated using this method. For 35 years, laser acupuncture in our country has been a standard in the treatment of a wide range of diseases, which is explained by high efficiency, and this, in turn, is due to correctly selected (justified) parameters (wavelength, power, time).
One of the main problems of modern LLLT is the difficulty in choosing the optimal parameters of the technique, and in our opinion, the exchange of experience will help specialists all over the world to get the right guidance for this purpose.
Materials and Methods
We conducted a narrative literature review on laser acupuncture. The main search was made in Russian libraries (the Russian Medical Library and the Russian State Library) – in Russian (1498 publications), and PubMed/Medline – in English (117 publications). 96 studies were selected for review according to the criteria for compliance with the requirements of Russian clinical recommendations on the optimal parameters of laser acupuncture techniques.
Understanding the methodology of laser acupuncture and substantiation of the optimal parameters of the technique (wavelength, spot size, power, modulation frequency range, etc) was formed several decades ago; therefore, references to fairly old works and monographs that combine numerous studies are used.
Results and Discussion
A total of 96 publications were analyzed, giving an opportunity to inform about the longest and most successful experience in applying the method.
Laser acupuncture is referred to as one of the reflexotherapy options in numerous thematic manuals and monographs.14,15 The essence of the technique consists in the activation of biologically active zones, also known as APs, by exposing them to low-intensity laser illumination. Microscopic light energies are required to activate APs. Therefore, the technique requires minimal laser power and exposure. Exceeding these values results in the suppression of the AP activity, and these points cease to “work.”
An AP is an area of the maximum activity of the integument-viscera interaction system that is projected onto the skin. AP physiological characteristics are specifically related to changes in the functional state of the internal organs and neural connections associated with them in the corresponding parts of the brain.
The sequence of AP localization and stimulation (the recipe) is chosen according to the principles of Traditional Chinese Medicine (TCM). However, in laser acupuncture techniques, the “classical” number of points is often reduced to simplify the procedure. The reduction in the number of points is not due to objective facts (increase in efficiency), but due to poor training in TCM. Laser acupuncture is increasingly used not by specialists in the field of acupuncture, but by doctors of completely different specialties, and even ordinary people.
To activate the desired AP rather than neighboring one that has other properties, a very small area no more than 1–1.5 mm in diameter needs to be illuminated. Special acupuncture nozzles attachments (Figure 1) are designed to concentrate the laser beam. These are also used for contact techniques (applied in dermatology and cosmetology).16
In the mid-1970s, a number of Russian researchers showed that when acting directly on nervous tissue, LLLT causes numerous responses, including modulation of the intact motor nerve excitability,17 changes in the neural firing rate,18 activation of synaptic processes, increased rate of elementary reactions and reduced time for excitation transfer from presynaptic to postsynaptic structures,19 neuron membrane depolarization, pulsed response potency acceleration and enhancement of bioenergetic processes,20 accelerated axonal growth (the process of axial cylinder myelination),21 and acceleration of peripheral nerve regeneration, restoration of its functions and bioelectric activity in a denervated skeletal muscle.22-25
These works formed the fundamental scientific basis to substantiate the techniques for stimulating the reflex zones and laser acupuncture. The technique was called “reflexotherapy”, focusing on the relationship between AP and the reflex response of the nervous system. There is a separate medical specialty, namely “doctor-reflexologist”, in Russia26; however, laser acupuncture can be carried out by other specialists, providing the medical service of “Laser puncture” (code: A17.01.002.03),27 guided by a rather wide range of indications and contraindications.28
Laser light is not only a very convenient alternative to traditional needles and the complicated manipulation techniques they require, but also a more efficient tool. The study by Denisova29 is of interest in this respect; the scholar directly compared the effectiveness of these three methods in patients suffering from gonarthrosis: classical acupuncture, AP exposure to electromagnetic radiation of the extremely high frequency (EHF) range, and LLLT. It was shown that laser exposure to EHF radiation is most preferred, while using laser light for acupuncture is also more effective than using traditional needles (Figure 2)30.
In comprehensive medical rehabilitation, the EHF-puncture technique is an alternative for children and hypersensitive patients as it is a non-invasive and painless technique with the ability to restore the functional balance of the meridian system as well as classical acupuncture is able to. In the comprehensive rehabilitation of patients with rheumatoid arthritis, it is preferable to conduct laser acupuncture for the purpose of pain relief.31 According to Avdey,32 in patients with osteochondrosis, the use of laser acupuncture is more preferable for a disease duration of up to 5 years, and EHF-puncture and needle acupuncture is more effective after 5 years.
It has been proven that APs are very sensitive to different physical (electromagnetic) fields. Systemic responses of the body, the direction of which depends on the energy parameters of the effect, are activated; that is, laser activation of TAs can have not only a tonic character, but also a tone-reducing character.
Features and advantages of laser acupuncture techniques:
small exposed zone (diameter ~1 mm)
exceptional ease of use
non-invasive, aseptic, comfortable procedure
possibility of using the technique by doctors of all medical specialties
accurate dosing of the exposure
minimum time required for the procedure
control over the reflex response direction
nonspecific pattern of receptor structure
ability to combine the technique with any type of treatment
high effectiveness.
Laser exposure does not cause subjective sensations in patients if the correct parameters of the technique are used. The phylo- and ontogenetic structure of the physiological processes in the human body determines a wide range of vegetative reactions of the body to AP bioactivation through the response of the ANS and the CNS, which has been proven by numerous studies.11,33
The point effect of the minimum energy of laser light in the AP zone results in the normalization of homeostasis due to the space-time summation.
The choice of the wavelength (635 nm) is explained by the penetration of light energy into the tissue at the optimum distance, deep enough for the desired structures to fall into the illumination zone. This is confirmed by our 35 years of practical experience,33 based on which the basic exposure scheme (recipe) for the normalization of sympathetic and parasympathetic regulation, activation of microcirculation is designed (Figure 3)33:
1-3-5 days of the week: LI4 (Hegu), ST36 (Zusanli) – symmetrically, CV12 (Zhongwan);
on Tuesday, Thursday and Saturday: PC6 (Neiguan), SP6 (Sanyinjiao) – symmetrically, CV12 (Zhongwan).
On Sunday, LLLT is not carried out.
Additional (hourly) APs can be used:
2 h – LR1 (Dadun)
4 h – LU8 (Jingqu)
6 h – LI1 (Shangyang)
8 h – ST36 (Zusanli)
10 h – SP3 (Taibai)
12 h – HT8 (Shaofu)
14 h – SI5 (Yanggu)
16 h – GV6 (Jizhong)
18 h – KI8 (Jiaoxin)
20 h – PС8 (Laogong)
22 h – TE6 (Zhigou)
24 h – GB41 (Zulinqi).
The order of exposure: first APs of the head, then the auricle, corporeal and distal APs. The doctor should be well aware of the localization of points and immediately place the acupuncture attachment on the desired APs with little pressure. In addition to the rules known to reflexologists, it is advisable to take into account some general neurophysiological connections.34
Table 1 presents the most optimal parameters for laser acupuncture. When exposed to corporal points with continuous or modulated red light (635 nm), the power at the end of the acupuncture attachment is 2–3 mW (without modulation) and 1–1.5 mW (with modulation).11 When exposed to auricular points, the green spectrum (525 nm) is used, since such illumination is absorbed much more strongly and scattering is minimal, which ensures the selectivity of the exposure.
Table 1. Parameters of Laser Acupuncture .
Parameter | Value | Note |
Wavelength, nm (spectrum) | 525 (green) | On auricular AP |
635 (red) | On corporal AP | |
Mode | Continuous or modulated | – |
F, Hz | In the recipe | Only for a modulated mode |
P*, mW | 0.5-1 | 525 nm |
2-3 | 635 nm | |
Time per 1 AP, s | 5-10 | Onto auricular AP |
20-40 | Onto corporal AP | |
Number of APs | Up to 15 | – |
Number of procedures | 5-12 | Daily |
* At the output of acupuncture attachment.
If the exposure is carried out in a modulated mode, the frequency is used from 1 to 10 Hz to achieve the stimulating effect, and 20-100 Hz for inhibition.35
Laser acupuncture is characterized by the inflexibility of the physical parameters of the technique: wavelength, power, and exposure time. Various aspects of laser acupuncture are discussed in detail in the review by Litscher and Opitz.36 Specifically, they cover the very important issue of optimizing the area of scattering over the surface and the laser light penetration depth depending on the wavelength. However, their work calls for some comments and clarifications. An interesting review is presented by Whittaker,3 who considered the prospects for the method and mechanisms for the implementation of the main effects.
The first task is to ensure the accuracy of the spatial characteristics of the technique. Laser emitting heads for devices of LASMIK series are intended to stimulate the corporal APs: KLΟ-635-5 (maximum power), or KLΟ-635-15 (reduced and controlled power) with an A-3 acupuncture attachment (light guide diameter not exceeding 1 mm). The APs are localized by doctors according to special atlases and guided by their own experience.
It is popularly believed that it is possible to determine the exact AP location by the minimum skin resistance with appropriate devices that are sold for this purpose. However, Kachan and Bogdanov,37 having examined the electrophysiological properties of APs, came to the conclusion that point localization by the amount of skin resistance to an electric current can be determined only very approximately since this indicator depends on the level of water-salt metabolism, blood circulation and microcirculation in the skin. Hyperemia and edema can also significantly change the skin electrical resistance, which, additionally, depends on the functional state of the nervous and endocrine systems (excited or depressed state of a person). Errors may also occur under the influence of external factors: season of the year and time of day, physical properties of the atmosphere, solar activity, nature of the contact, humidity, parameters of the probing signal, and so forth. Therefore, it is unacceptable to localize APs by this method.
The wavelength is the most important parameter of any LLLT technique. Previously almost all clinicians used to apply helium-neon laser light (633 nm laser wavelength, 2-6 mW power) for laser acupuncture. The work by Buylin,38 is an exception; the scholar used infrared (IR) laser diodes with a 1264 nm wavelength, which is close to the second harmonic of red light (633 nm × 2 = 1266 nm). The author relied on the “theory of singlet oxygen” in his choice mentioned in the first part of the book. It seems likely that this was also a verification of the option proposed by Romodanov et al,39 who paid attention to the identity of laser illumination and moxibustion, an ancient Chinese method of burning dried mugwort on particular points on the body, having one of the maxima of its luminous spectrum in this area ≈1300 nm. However, since it is preferable to see the place of the illumination to obtain a guaranteed and reproducible result, infrared (that is, invisible) LLLT was abandoned.
To choose the wavelength is also important for the technique because of purely biophysical considerations, since it is necessary to take into account the substantial differences in the depth at which the APs are located and their proximity to each other. The accuracy of exposure localization is important for very closely spaced APs (auricular points). That is why LLLT is used in the green range (525 nm), as the absorption at this wavelength is significantly higher than in the red region of the spectrum.40 Accordingly, irradiation scattering is reduced, the illumination area is limited, which ensures the required selectivity (positioning and localization accuracy), and only the necessary points are exposed as required by the method, without significant impact on other APs located nearby.
For example, Branco and Naeser41 recommend to use a red laser (633 nm, 15 mW) for patients with carpal tunnel syndrome to stimulate APs nearby the skin surface, and pulsed infrared (905 nm, 9 W pulsed power) to illuminate deep-seated affected tissues and organs. There are publications in which other wavelength values were used to stimulate corporal APs: 405 nm,36 658 nm,42 670 nm,43 685 nm,36,44 830 nm,45,46 950 nm,47 and so on. But the parameters specified in Table 1 are most optimal.
Laser power is another important parameter. We emphasize again that power of no more than 2-3 mW should be used for laser acupuncture! It is not uncommon to find completely insane recommendations in the literature regarding the performance to be used.
For example, Kneebone48 recommends to relieve pain by illuminating APs with a “red laser” (no wavelength indicated) for 30–60 s at a power of 5–20 mW, for 10–20 s at 50–250 mW and for 5 –10 s at 500 mW and more (ranging from 2 to 4 min per 1 session)! For reference, local exposure at 500 mW (it is frightful even to think about “greater” values) will result in a severe burn. Let us refer to one of the publications, as an example of what and how should not be done in any case when performing laser acupuncture, and laser therapy in general.49 All parameters are extremely far from the permissible ones.
Many years ago it was shown that exposure time for laser acupuncture (633-635 nm wavelength, 2-3 mW) should be limited to 30-40 s, in contrast to classical acupuncture, where completely different temporal parameters (5-15 min) are applied.8 Currently, continuous LLLT (635 nm wavelength, 2–3 mW output power at an acupuncture nozzle to be controlled obligatorily) is most often used to illuminate corporal APs with an exposure time not exceeding 20–40 s per a point.11,33 Leontyuk et al50 pay attention to the age-related features of the response of some organs of the endocrine, immune and sympathoadrenal systems after laser acupuncture and strongly recommend to consider the patient’s age when prescribing this procedure. This refers to the recipe adjustment.
Laser acupuncture is an integral part of LLLT; it has long and widely been used in practical healthcare in Russia and other countries. This is only a small list of relevant publications in the main areas of medicine:
angiology57;
infectious diseases73;
sports medicine97;
phthisiology (the care, treatment, and study of tuberculosis)102-104;
The optimal parameters of the technique were worked out by Russian specialists in the 70 s of the last century, and all these years the conclusions drawn are perfectly confirmed by the wide practice of clinical application. If you change the optimal values of the wavelength, power, and most importantly the exposure, then the APs either do not respond properly, for example, when the power decreases, or stop responding to any stimulus after some time at high power.
The size and format of the article do not allow a detailed examination of each study; there are a lot of them and most of them were carried out with a placebo when there was the contact of the special acupuncture nozzle and the laser was not turned on. In addition, over 35 years of mass use of the method, there were many opportunities and proposals for changing the parameters of the methodology that we presented above, and all of them did not receive recognition. This certainly confirms the correctness of our recommendations.
Conclusion
In summary, laser acupuncture has gained a reputation of a highly effective and reproducible technique for treating patients with the widest range of diseases; any specialists can apply this method because of its simplicity, but using the most effective parameters (wavelength, mode of operation, power, illuminated area and exposure time).
The literature analysis shows that it is most optimal to conduct 5-12 daily laser acupuncture procedures with a wavelength of 635 nm (red spectrum), power of no more than 2-3 mW, exposure of 20-40 s for corporal points and 5-10 s for auricular points. The impact on APs is carried out consistently in accordance with the recipe (protocol).
The effectiveness of laser acupuncture is beyond doubt,109-112 and it is necessary to make it as effective as possible with reproducible treatment results.
Ethical Considerations
Not applicable.
Conflict of Interests
The authors declare no conflict of interest.
Please cite this article as follows: Moskvin SV, Agasarov LG. Laser acupuncture: 35 years of successful application in Russia (narrative review). J Lasers Med Sci. 2020;11(4):381-389. doi:10.34172/jlms.2020.61.
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