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. 2020 Dec 1;43(6):209. doi: 10.18773/austprescr.2020.075

Top 10 drugs 2019–20

PMCID: PMC7738697  PMID: 33363304

Tables 1, 2 and 3 show the top 10 drugs for the year July 2019 – June 2020. The figures are based on PBS and RPBS prescriptions from the date of supply. The figures include prescriptions under the co-payment (non-subsidised).

Table 1. Top 10 PBS/RPBS drugs by DDD/1000 population/day.

Drug DDD/1000 pop/day*
1. atorvastatin 72.93
2. rosuvastatin 61.03
3. perindopril 52.34
4. amlodipine 50.15
5. candesartan 33.52
6. telmisartan 32.19
7. irbesartan 29.87
8. ramipril 26.44
9. sertraline 25.67
10. metformin 25.51

Table 2. Top 10 PBS/RPBS drugs by prescription counts.

Drug Prescriptions
1. rosuvastatin 12,968,693
2. atorvastatin 11,241,737
3. pantoprazole 8,283,205
4. esomeprazole 8,171,291
5. perindopril 6,688,735
6. cefalexin 5,347,062
7. metformin 5,183,224
8. escitalopram 4,983,887
9. amoxicillin 4,777,911
10. sertraline 4,714,321

Table 3. Top 10 PBS/RPBS drugs by cost to government (does not include rebates).

Drug Cost to government DDD/1000 pop/day* Prescriptions
1. aflibercept $392,045,570 315,200
2. nivolumab $344,751,398 51,882
3. pembrolizumab $342,875,272 38,860
4. adalimumab $320,969,041 0.76 257,328
5. denosumab $244,407,111 18.44 884,413
6. sofosbuvir + velpatasvir† $223,484,429 17,733
7. ranibizumab $218,085,96 190,126
8. ustekinumab $211,250,971 0.49 29,603
9. apixaban $210,022,698 6.81 2,580,428
10. glecaprevir + pibrentasvir† $186,730,613 9,956

DDD defined daily dose

PBS Pharmaceutical Benefits Scheme

RPBS Repatriation Pharmaceutical Benefits Scheme

* DDD/thousand population/day is a more useful measure of drug utilisation than prescription counts. It shows how many people in every thousand Australians are taking the standard dose of a drug every day. DDD includes use in combination products. The calculation is based on ABS 3101.0 – Australian Demographic Statistics for December 2019.

† DDDs for combination products are accounted for in constituent drugs

‡ The World Health Organization has not allocated a DDD for this drug

     Source: Department of Health, December 2020. ©Commonwealth of Australia


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