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. 2021 Jan 1;11(3):1079–1099. doi: 10.7150/thno.49354

Figure 1.

Figure 1

miR-802 expression is decreased in mice infected with S. japonicum. (A-B) Five mixed liver samples from ND-con and ND-inf mice in each group were utilized to analyze a comprehensive microRNA by the miRNA microarray chip. (A) 10 up-regulated and 10 down-regulated miRNAs in the liver miRNA microarray chip were selected. (B) Enriched signaling pathways of the top 40 target genes of miR-802. (C) miR-802 expression by qRT-PCR in livers of ND-con mice at 0w, 3w, 6w, 9w, and 12w after S. japonicum infection. (D) miR-802 expression by qRT-PCR in sera of C57BL/6 mice at different time-points post infection. (E) qRT-PCR quantification of miR-802 expression in the livers of uninfected and infected C57BL/6 mice fed with a normal chow diet and high fat diet. Data are expressed as the mean ± s.e.m of 6 mice for each group in one representative experiment. All experiments were repeated twice, *P <0.05, **P <0.01, ***P <0.001.